Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2069567..2069712 Replicon chromosome
Accession NZ_CP082032
Organism Klebsiella pneumoniae strain KP18-2138

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2069603..2069705 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2069567..2069712 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6163_RS10200 2064697..2066757 + 2061 WP_004151449.1 oligopeptidase B -
K6163_RS10205 2066761..2067420 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6163_RS10210 2067499..2067729 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6163_RS10215 2067842..2068216 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6163_RS10220 2068220..2069089 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K6163_RS10225 2069106..2069444 + 339 WP_002911404.1 YebY family protein -
- 2069567..2069712 - 146 - - Antitoxin
- 2069603..2069705 + 103 - - Toxin
K6163_RS10230 2070080..2070223 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6163_RS10235 2070328..2071296 - 969 WP_004151446.1 VirK/YbjX family protein -
K6163_RS10240 2071453..2072106 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K6163_RS10245 2072103..2072294 - 192 WP_002911395.1 YebW family protein -
K6163_RS10250 2072392..2072631 - 240 WP_002911393.1 YebV family protein -
K6163_RS10255 2072747..2074180 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214035 NZ_CP082032:2069603-2069705 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214035 NZ_CP082032:c2069712-2069567 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References