Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2166645..2166790 Replicon chromosome
Accession NZ_CP082029
Organism Klebsiella pneumoniae strain KP18-2113

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2166681..2166783 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2166645..2166790 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6164_RS10535 2161775..2163835 + 2061 WP_004151449.1 oligopeptidase B -
K6164_RS10540 2163839..2164498 - 660 WP_020324964.1 exodeoxyribonuclease X -
K6164_RS10545 2164577..2164807 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6164_RS10550 2164920..2165294 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6164_RS10555 2165298..2166167 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6164_RS10560 2166184..2166522 + 339 WP_002911404.1 YebY family protein -
- 2166645..2166790 - 146 - - Antitoxin
- 2166681..2166783 + 103 - - Toxin
K6164_RS10565 2167159..2167302 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6164_RS10570 2167407..2168375 - 969 WP_004151446.1 VirK/YbjX family protein -
K6164_RS10575 2168532..2169185 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K6164_RS10580 2169182..2169373 - 192 WP_002911395.1 YebW family protein -
K6164_RS10585 2169471..2169710 - 240 WP_002911393.1 YebV family protein -
K6164_RS10590 2169826..2171259 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214011 NZ_CP082029:2166681-2166783 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214011 NZ_CP082029:c2166790-2166645 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References