Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2071482..2071627 Replicon chromosome
Accession NZ_CP082024
Organism Klebsiella pneumoniae strain KP18-2073

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2071518..2071620 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2071482..2071627 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6166_RS10245 2066612..2068672 + 2061 WP_004151449.1 oligopeptidase B -
K6166_RS10250 2068676..2069335 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6166_RS10255 2069414..2069644 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6166_RS10260 2069757..2070131 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6166_RS10265 2070135..2071004 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K6166_RS10270 2071021..2071359 + 339 WP_002911404.1 YebY family protein -
- 2071482..2071627 - 146 - - Antitoxin
- 2071518..2071620 + 103 - - Toxin
K6166_RS10275 2071995..2072138 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6166_RS10280 2072243..2073211 - 969 WP_004151446.1 VirK/YbjX family protein -
K6166_RS10285 2073368..2074021 + 654 WP_206640633.1 protein-serine/threonine phosphatase -
K6166_RS10290 2074018..2074209 - 192 WP_002911395.1 YebW family protein -
K6166_RS10295 2074307..2074546 - 240 WP_002911393.1 YebV family protein -
K6166_RS10300 2074662..2076095 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213977 NZ_CP082024:2071518-2071620 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213977 NZ_CP082024:c2071627-2071482 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References