Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2073313..2073458 Replicon chromosome
Accession NZ_CP082019
Organism Klebsiella pneumoniae strain KP18-2050

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2073349..2073451 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2073313..2073458 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6159_RS10260 2068443..2070503 + 2061 WP_004151449.1 oligopeptidase B -
K6159_RS10265 2070507..2071166 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6159_RS10270 2071245..2071475 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6159_RS10275 2071588..2071962 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6159_RS10280 2071966..2072835 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K6159_RS10285 2072852..2073190 + 339 WP_002911404.1 YebY family protein -
- 2073313..2073458 - 146 - - Antitoxin
- 2073349..2073451 + 103 - - Toxin
K6159_RS10290 2073826..2073969 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6159_RS10295 2074074..2075042 - 969 WP_004151446.1 VirK/YbjX family protein -
K6159_RS10300 2075199..2075852 + 654 WP_206640633.1 protein-serine/threonine phosphatase -
K6159_RS10305 2075849..2076040 - 192 WP_002911395.1 YebW family protein -
K6159_RS10310 2076138..2076377 - 240 WP_002911393.1 YebV family protein -
K6159_RS10315 2076493..2077926 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213946 NZ_CP082019:2073349-2073451 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213946 NZ_CP082019:c2073458-2073313 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References