Detailed information of TA system TA021393

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2888568..2889124
• Replicon: chromosome
• Accession: NC_007705
• Organism: Xanthomonas oryzae pv. oryzae MAFF 311018

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: TX61_RS13480
• Protein ID: WP_027703932.1
• Coordinates: 2888568..2888858 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: TX61_RS13485
• Protein ID: WP_011408759.1
• Coordinates: 2888846..2889124 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
TX61_RS13445	2884338..2885429	+	1092	WP_011408756.1	ribonuclease D	-
TX61_RS13450	2885526..2885842	-	317	Protein_2598	ATP-dependent DNA ligase	-
TX61_RS28225	2885902..2886108	-	207	Protein_2599	hypothetical protein	-
TX61_RS28380	2886124..2886300	-	177	Protein_2600	DUF3606 domain-containing protein	-
TX61_RS13460	2886522..2886923	+	402	WP_011259345.1	H-NS histone family protein	-
TX61_RS13470	2887787..2887966	-	180	WP_015463309.1	hypothetical protein	-
TX61_RS28655	2888110..2888307	-	198	WP_153296741.1	hypothetical protein	-
TX61_RS13480	2888568..2888858	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
TX61_RS13485	2888846..2889124	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
TX61_RS28580	2889205..2889408	-	204	WP_199285669.1	hypothetical protein	-
TX61_RS28585	2889320..2889706	-	387	WP_205412094.1	hypothetical protein	-
TX61_RS25295	2889609..2889809	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
TX61_RS13490	2890570..2891754	-	1185	WP_011408760.1	IS256 family transposase	-
TX61_RS13495	2892335..2893300	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
TX61_RS25300	2893402..2894007	+	606	Protein_2611	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T21393 WP_027703932.1 NC_007705:c2888858-2888568 [Xanthomonas oryzae pv. oryzae MAFF 311018]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T21393 NC_007705:c2888858-2888568 [Xanthomonas oryzae pv. oryzae MAFF 311018]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT21393 WP_011408759.1 NC_007705:c2889124-2888846 [Xanthomonas oryzae pv. oryzae MAFF 311018]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT21393 NC_007705:c2889124-2888846 [Xanthomonas oryzae pv. oryzae MAFF 311018]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2