Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2144413..2144558 Replicon chromosome
Accession NZ_CP082005
Organism Klebsiella pneumoniae strain KP18-8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2144449..2144551 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2144413..2144558 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6148_RS11025 2139543..2141603 + 2061 WP_004151449.1 oligopeptidase B -
K6148_RS11030 2141607..2142266 - 660 WP_020324964.1 exodeoxyribonuclease X -
K6148_RS11035 2142345..2142575 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6148_RS11040 2142688..2143062 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6148_RS11045 2143066..2143935 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6148_RS11050 2143952..2144290 + 339 WP_002911404.1 YebY family protein -
- 2144413..2144558 - 146 - - Antitoxin
- 2144449..2144551 + 103 - - Toxin
K6148_RS11055 2144927..2145070 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6148_RS11060 2145175..2146143 - 969 WP_004151446.1 VirK/YbjX family protein -
K6148_RS11065 2146300..2146953 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K6148_RS11070 2146950..2147141 - 192 WP_002911395.1 YebW family protein -
K6148_RS11075 2147239..2147478 - 240 WP_002911393.1 YebV family protein -
K6148_RS11080 2147594..2149027 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213869 NZ_CP082005:2144449-2144551 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213869 NZ_CP082005:c2144558-2144413 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References