Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2071471..2071616 Replicon chromosome
Accession NZ_CP082001
Organism Klebsiella pneumoniae strain KP18-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2071507..2071609 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2071471..2071616 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6149_RS10250 2066601..2068661 + 2061 WP_004151449.1 oligopeptidase B -
K6149_RS10255 2068665..2069324 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6149_RS10260 2069403..2069633 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6149_RS10265 2069746..2070120 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6149_RS10270 2070124..2070993 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K6149_RS10275 2071010..2071348 + 339 WP_002911404.1 YebY family protein -
- 2071471..2071616 - 146 - - Antitoxin
- 2071507..2071609 + 103 - - Toxin
K6149_RS10280 2071984..2072127 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6149_RS10285 2072232..2073200 - 969 WP_004151446.1 VirK/YbjX family protein -
K6149_RS10290 2073357..2074010 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K6149_RS10295 2074007..2074198 - 192 WP_002911395.1 YebW family protein -
K6149_RS10300 2074296..2074535 - 240 WP_002911393.1 YebV family protein -
K6149_RS10305 2074651..2076084 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213839 NZ_CP082001:2071507-2071609 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213839 NZ_CP082001:c2071616-2071471 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References