Detailed information of TA system TA213829

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 2124498..2124984
• Replicon: chromosome
• Accession: NZ_CP081987
• Organism: Shinella oryzae strain Z-25

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: K6301_RS10445
• Protein ID: WP_247216690.1
• Coordinates: 2124498..2124767 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: K6301_RS10450
• Protein ID: WP_247216692.1
• Coordinates: 2124751..2124984 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K6301_RS10425 (K6301_10420)	2119580..2120086	+	507	WP_247216683.1	DUF1993 domain-containing protein	-
K6301_RS10430 (K6301_10425)	2120139..2121818	-	1680	WP_247216684.1	formate--tetrahydrofolate ligase	-
K6301_RS10435 (K6301_10430)	2122037..2123185	-	1149	WP_247216687.1	DUF2333 family protein	-
K6301_RS10440 (K6301_10435)	2123178..2124479	-	1302	WP_247216688.1	hypothetical protein	-
K6301_RS10445 (K6301_10440)	2124498..2124767	-	270	WP_247216690.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K6301_RS10450 (K6301_10445)	2124751..2124984	-	234	WP_247216692.1	DUF6290 family protein	Antitoxin
K6301_RS10455 (K6301_10450)	2125054..2126964	-	1911	WP_247216694.1	AAA family ATPase	-
K6301_RS10460 (K6301_10455)	2127014..2128162	-	1149	WP_247216696.1	hypothetical protein	-
K6301_RS10465 (K6301_10460)	2128368..2129456	-	1089	WP_247216698.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-88)

Antitoxin

• Ribbon-helix-helix protein, CopG (6-41)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10225.87 Da
• Isoelectric Point: 10.3650

>T213829 WP_247216690.1 NZ_CP081987:c2124767-2124498 [Shinella oryzae]
MAWAIEITEGAKKELDKLGHVEAKRIRNFLVTKLASSENPRLLGSALQGARLGSYWRYRVGDYRIICDIQDNRLVVVVVR
VGHRREIYS

Nucleotide

• Length: 270 bp

>T213829 NZ_CP109874:c4610221-4610048 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGCGCATTCCTGGTCGGAATAACCTGGCCAATGAGTTTACCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8986.00 Da
• Isoelectric Point: 4.3640

>AT213829 WP_247216692.1 NZ_CP081987:c2124984-2124751 [Shinella oryzae]
MAKQTAIRLPDETYERLQALAARTGRTATYYIREAIEQHIEDLEDIYLAEQELERVRRGESRVYSLKEVEDELGLGD

Nucleotide

• Length: 234 bp

>AT213829 NZ_CP109874:c4610545-4610249 [Escherichia coli]
ATGGAAGGTAAAAATAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACCGTTGATGACTATTTCCGTCAGTTTTACAAGTAG