213818

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT_toxin-BrnA
Location 4784801..4785305 Replicon chromosome
Accession NZ_CP081944
Organism Pseudomonas sp. DR208

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag K5K89_RS21440 Protein ID WP_222540223.1
Coordinates 4785075..4785305 (-) Length 77 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag K5K89_RS21435 Protein ID WP_222540222.1
Coordinates 4784801..4785049 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5K89_RS21415 (K5K89_21415) 4780512..4781315 + 804 WP_222540221.1 alpha/beta hydrolase -
K5K89_RS21420 (K5K89_21420) 4781319..4781882 + 564 WP_071491351.1 peptidylprolyl isomerase -
K5K89_RS21425 (K5K89_21425) 4781965..4783797 + 1833 WP_071491352.1 ABC transporter ATP-binding protein -
K5K89_RS21430 (K5K89_21430) 4784044..4784745 + 702 WP_093529419.1 aquaporin Z -
K5K89_RS21435 (K5K89_21435) 4784801..4785049 - 249 WP_222540222.1 BrnA antitoxin family protein Antitoxin
K5K89_RS21440 (K5K89_21440) 4785075..4785305 - 231 WP_222540223.1 BrnT family toxin Toxin
K5K89_RS21445 (K5K89_21445) 4785382..4786506 - 1125 WP_222540224.1 GNAT family N-acetyltransferase -
K5K89_RS21450 (K5K89_21450) 4786789..4788111 + 1323 WP_028617432.1 putative porin -
K5K89_RS21455 (K5K89_21455) 4788219..4788464 - 246 WP_071491356.1 zf-HC2 domain-containing protein -
K5K89_RS21460 (K5K89_21460) 4788458..4789072 - 615 WP_071491357.1 RNA polymerase sigma factor -
K5K89_RS21465 (K5K89_21465) 4789090..4790211 - 1122 WP_071491358.1 beta-ketoacyl-ACP synthase III -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4784801..4795624 10823


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-76)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(33-77)


Sequences

Toxin        


Download         Length: 77 a.a.        Molecular weight: 8879.22 Da        Isoelectric Point: 6.7239

>T213818 WP_222540223.1 NZ_CP081944:c4785305-4785075 [Pseudomonas sp. DR208]
MLFEWDESKNKANIVKHGIDFNDVPDIFRHPMLALRDDRADYGEERWISIGWIKLLVGVVVYTERHGGVIRIISAR

Download         Length: 231 bp

>T213818 NZ_CP109874:2879447-2879554 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9611.72 Da        Isoelectric Point: 4.7497

>AT213818 WP_222540222.1 NZ_CP081944:c4785049-4784801 [Pseudomonas sp. DR208]
MTQTSKTDWERLAKMNDNEIDTSDIPELDADFFRHADLRVPVKQAVTIRLDADVLEWFKDQGSGYQTRINQLLRQYMQAH
QG

Download         Length: 249 bp

>AT213818 NZ_CP109874:c2879394-2879333 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References