Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 111190..111730 Replicon chromosome
Accession NZ_CP081939
Organism Avibacterium paragallinarum strain p4chr1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K5O18_RS00555 Protein ID WP_110479397.1
Coordinates 111440..111730 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K5O18_RS00550 Protein ID WP_110479398.1
Coordinates 111190..111450 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5O18_RS00525 (K5O18_00525) 106369..106533 - 165 WP_165816430.1 hypothetical protein -
K5O18_RS00530 (K5O18_00530) 106604..107185 + 582 WP_017806819.1 D-sedoheptulose 7-phosphate isomerase -
K5O18_RS00535 (K5O18_00535) 107275..108681 + 1407 WP_110479400.1 membrane-bound lytic murein transglycosylase MltF -
K5O18_RS00545 (K5O18_00545) 109568..110755 + 1188 WP_110479399.1 tyrosine-type recombinase/integrase -
K5O18_RS00550 (K5O18_00550) 111190..111450 + 261 WP_110479398.1 stability protein StbD Antitoxin
K5O18_RS00555 (K5O18_00555) 111440..111730 + 291 WP_110479397.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K5O18_RS00560 (K5O18_00560) 112467..112757 + 291 WP_017806817.1 co-chaperone GroES -
K5O18_RS00565 (K5O18_00565) 112830..114473 + 1644 WP_110479396.1 chaperonin GroEL -
K5O18_RS00570 (K5O18_00570) 114756..115703 - 948 WP_110479395.1 cysteine synthase A -
K5O18_RS00575 (K5O18_00575) 115822..116670 - 849 WP_110479394.1 sulfate transporter CysZ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11418.36 Da        Isoelectric Point: 10.7313

>T213799 WP_110479397.1 NZ_CP081939:111440-111730 [Avibacterium paragallinarum]
MTYKLSFDKRALKEWHKLGDTLRQQFKAKLIERLENPHVLSDKLHGYQTLYKIKLRSAGYRLVYDVNDNEIRVIVLSVGK
RERLQAYKKALSRKAQ

Download         Length: 291 bp

>T213799 NZ_CP109856:1867261-1867848 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAATTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9604.03 Da        Isoelectric Point: 4.3085

>AT213799 WP_110479398.1 NZ_CP081939:111190-111450 [Avibacterium paragallinarum]
MAIQQILTRHTASISDLKKNPMGIVSEGTEQEGAIAILNRNEPVFYCVNPRLFAVIQEILEDKELGELATQRLATLDPVE
VRLDDL

Download         Length: 261 bp

>AT213799 NZ_CP109856:1867915-1868769 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCCGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCACGTGCACAGCAGCTTCGCCCTGGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTGGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAAATGGAGCAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGCGTGCCGCGTTTCGCCGACAGCGTGATCCACGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGACCCGCTGGCGCGAGACGATGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCCCGCGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCGCTGGAGGAACTGGCGGCGGCGGTCAATCTGTCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGGCAGCGCCGCCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGCTGGAGGTGGCCCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGGCCTACGGGGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCGTCCTTGACGACATACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References