Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/Txe-RelB
Location 6256043..6256563 Replicon chromosome
Accession NZ_CP081903
Organism Bacteroides cellulosilyticus strain BFG-250

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K6V21_RS24090 Protein ID WP_224320138.1
Coordinates 6256294..6256563 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag K6V21_RS24085 Protein ID WP_224320137.1
Coordinates 6256043..6256297 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6V21_RS24065 (K6V21_23965) 6251095..6251649 - 555 WP_217714731.1 RNA polymerase sigma-70 factor -
K6V21_RS24070 (K6V21_23970) 6251807..6253552 + 1746 WP_224320136.1 pectate lyase -
K6V21_RS24075 (K6V21_23975) 6253728..6254429 + 702 WP_007664170.1 nitrogen-fixing protein NifU -
K6V21_RS24080 (K6V21_23980) 6254449..6255459 + 1011 WP_022392200.1 GGGtGRT protein -
K6V21_RS24085 (K6V21_23985) 6256043..6256297 + 255 WP_224320137.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
K6V21_RS24090 (K6V21_23990) 6256294..6256563 + 270 WP_224320138.1 Txe/YoeB family addiction module toxin Toxin
K6V21_RS24095 (K6V21_23995) 6257135..6258733 + 1599 WP_224320139.1 leucine-rich repeat domain-containing protein -
K6V21_RS24100 (K6V21_24000) 6259483..6261441 + 1959 WP_224320140.1 LruC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10844.65 Da        Isoelectric Point: 10.1205

>T213797 WP_224320138.1 NZ_CP081903:6256294-6256563 [Bacteroides cellulosilyticus]
MKVIFSPLAMEQWEYWKKNNPNIAKRIKKILLDIREHPYTGIAKPEPLKYDLAGKWSRRINEEHRIIYSVNDDRIEIDIL
SMRYHYSKK

Download         Length: 270 bp

>T213797 NZ_CP109854:c641032-640697 [Pantoea dispersa]
GTGACGGGTAATTATCTGGAATTTATCGAAACGCGCGTGTTTTCAAAAGCTCGTCAGAGTCTGCTGGCAGACGATCAAGA
ATTTCAGGAACTGCAAATTTTTTTGCTTGAGCATCATGAGTTAGGTGACACCATTAGTCAGACCGGAGGATGCAAAAAGA
TTCGCTGGAGCCGGGCCGGAATGGGTAAACGTGGTGGAACAAGGATTATTTATTACACCCGCCTGAGCTCAGGCAGAATT
TATCTGTTACTCATCTATCCCAAAAATGTGAAGGATGATTTAAATGAAGCAGAAAAAGCGTTGCTAAAAGTCTTTACCCA
ACAAATGAACCTCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9406.50 Da        Isoelectric Point: 4.0721

>AT213797 WP_224320137.1 NZ_CP081903:6256043-6256297 [Bacteroides cellulosilyticus]
MRTANYTDLRANLKGYIDSVIDDYDTVIVNRGNGKGVVMISLDEYNSLKETEYIMSSPATMEAIRQGEEDIKNGKGIEVD
LDEL

Download         Length: 255 bp

>AT213797 NZ_CP109854:c640671-640375 [Pantoea dispersa]
ATGGAAAAACAGCTATTTAATGACCTGCTGGAAAGCGTACAGGAAATGGTCGCCATTGAGCAGGGTCATGAATCACCGGA
TATGAACCGCGTCCACCGTCATGAACTGCCGGATGTAAAGCTGATCAGAAAGAATGCTGGGCTAAAACAAGTTGAATTTG
CCCATGCGATGGGCGTTAGCGTGGATCTTATTCGTAGCTGGGAGCAGCACAGACGCAACCCTACCGGTCCAGCATTGAAA
ATGCTTTATCTGATTCAGCAGCAGCCATTACTCATCAATGCTTTACAGGCGCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References