Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1827362..1827507 Replicon chromosome
Accession NZ_CP081897
Organism Klebsiella pneumoniae strain MN-03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1827398..1827500 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1827362..1827507 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ659_RS08875 (KZ659_08865) 1822492..1824552 + 2061 WP_004148850.1 oligopeptidase B -
KZ659_RS08880 (KZ659_08870) 1824556..1825215 - 660 WP_002911407.1 exodeoxyribonuclease X -
KZ659_RS08885 (KZ659_08875) 1825294..1825524 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KZ659_RS08890 (KZ659_08880) 1825637..1826011 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KZ659_RS08895 (KZ659_08885) 1826015..1826884 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
KZ659_RS08900 (KZ659_08890) 1826901..1827239 + 339 WP_002911404.1 YebY family protein -
- 1827362..1827507 - 146 - - Antitoxin
- 1827398..1827500 + 103 - - Toxin
KZ659_RS08905 (KZ659_08895) 1827875..1828018 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KZ659_RS08910 (KZ659_08900) 1828123..1829091 - 969 WP_014907334.1 VirK/YbjX family protein -
KZ659_RS08915 (KZ659_08905) 1829248..1829901 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
KZ659_RS08920 (KZ659_08910) 1829898..1830089 - 192 WP_002911395.1 YebW family protein -
KZ659_RS08925 (KZ659_08915) 1830187..1830426 - 240 WP_002911393.1 YebV family protein -
KZ659_RS08930 (KZ659_08920) 1830542..1831975 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213782 NZ_CP081897:1827398-1827500 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213782 NZ_CP081897:c1827507-1827362 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References