Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1821277..1821422 Replicon chromosome
Accession NZ_CP081896
Organism Klebsiella pneumoniae strain PA-01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1821313..1821415 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1821277..1821422 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ665_RS08775 (KZ665_08775) 1816407..1818467 + 2061 WP_004151449.1 oligopeptidase B -
KZ665_RS08780 (KZ665_08780) 1818471..1819130 - 660 WP_002911407.1 exodeoxyribonuclease X -
KZ665_RS08785 (KZ665_08785) 1819209..1819439 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KZ665_RS08790 (KZ665_08790) 1819552..1819926 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KZ665_RS08795 (KZ665_08795) 1819930..1820799 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
KZ665_RS08800 (KZ665_08800) 1820816..1821154 + 339 WP_002911404.1 YebY family protein -
- 1821277..1821422 - 146 - - Antitoxin
- 1821313..1821415 + 103 - - Toxin
KZ665_RS08805 (KZ665_08805) 1821790..1821933 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KZ665_RS08810 (KZ665_08810) 1822038..1823006 - 969 WP_004151446.1 VirK/YbjX family protein -
KZ665_RS08815 (KZ665_08815) 1823163..1823816 + 654 WP_023285311.1 protein-serine/threonine phosphatase -
KZ665_RS08820 (KZ665_08820) 1823813..1824004 - 192 WP_002911395.1 YebW family protein -
KZ665_RS08825 (KZ665_08825) 1824102..1824341 - 240 WP_002911393.1 YebV family protein -
KZ665_RS08830 (KZ665_08830) 1824457..1825890 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213763 NZ_CP081896:1821313-1821415 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213763 NZ_CP081896:c1821422-1821277 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References