Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1914711..1914856 Replicon chromosome
Accession NZ_CP081894
Organism Klebsiella pneumoniae strain NC-01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1914747..1914849 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1914711..1914856 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ666_RS09275 1909841..1911901 + 2061 WP_032429395.1 oligopeptidase B -
KZ666_RS09280 1911905..1912564 - 660 WP_002911407.1 exodeoxyribonuclease X -
KZ666_RS09285 1912643..1912873 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KZ666_RS09290 1912986..1913360 + 375 WP_023286640.1 CopC domain-containing protein YobA -
KZ666_RS09295 1913364..1914233 + 870 WP_023286639.1 copper homeostasis membrane protein CopD -
KZ666_RS09300 1914250..1914588 + 339 WP_016529031.1 YebY family protein -
- 1914711..1914856 - 146 - - Antitoxin
- 1914747..1914849 + 103 - - Toxin
KZ666_RS09305 1915223..1915366 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KZ666_RS09310 1915471..1916439 - 969 WP_074194451.1 VirK/YbjX family protein -
KZ666_RS09315 1916596..1917249 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
KZ666_RS09320 1917246..1917437 - 192 WP_002911395.1 YebW family protein -
KZ666_RS09325 1917535..1917774 - 240 WP_002911393.1 YebV family protein -
KZ666_RS09330 1917890..1919323 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213731 NZ_CP081894:1914747-1914849 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213731 NZ_CP081894:c1914856-1914711 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References