Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 4894223..4895904 Replicon chromosome
Accession NZ_CP081893
Organism Klebsiella quasipneumoniae strain WI-06

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag KZ658_RS23590 Protein ID WP_040971114.1
Coordinates 4894223..4895140 (-) Length 306 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag KZ658_RS23595 Protein ID WP_223065544.1
Coordinates 4895146..4895904 (-) Length 253 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ658_RS23570 (4889529) 4889529..4891049 + 1521 WP_044525151.1 sugar ABC transporter ATP-binding protein -
KZ658_RS23575 (4891046) 4891046..4892044 + 999 WP_223065542.1 ribose ABC transporter permease -
KZ658_RS23580 (4892075) 4892075..4893016 + 942 WP_023291657.1 ABC transporter substrate-binding protein -
KZ658_RS23585 (4893091) 4893091..4894098 + 1008 WP_223065543.1 carbohydrate kinase family protein -
KZ658_RS23590 (4894223) 4894223..4895140 - 918 WP_040971114.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
KZ658_RS23595 (4895146) 4895146..4895904 - 759 WP_223065544.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
KZ658_RS23600 (4895989) 4895989..4896717 - 729 WP_223065545.1 response regulator transcription factor -
KZ658_RS23605 (4896990) 4896990..4899137 + 2148 WP_077598907.1 formate dehydrogenase subunit alpha -
KZ658_RS23610 (4899451) 4899451..4900137 + 687 WP_023291654.1 tetratricopeptide repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-278)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-93)


Sequences

Toxin        


Download         Length: 306 a.a.        Molecular weight: 34737.11 Da        Isoelectric Point: 5.4707

>T213728 WP_040971114.1 NZ_CP081893:c4895140-4894223 [Klebsiella quasipneumoniae]
MDIQAPYYRQVALLMQVLPYVAVEREFALKGGTAINLFIRDFPRLSVDIDLAWVPLESRTIALPHIRDALARIAANLQQQ
AGMNAVLQANRSDEMRVVVTTDSAQIKIEVSPVARGTLYPPQEREVVGAVEDVFGYASLPVVSLPDLYGGKLCAALDRQH
PRDFYDVKLLLDAQELNRPIFNGFIAYLLSHNRPLAEVLSPRWKDIAEPFYREFSGMTFETIALEELTAVPYRMIDALKS
CFTQQDVDFLLSFKRGEPDWRLAPETRIQDLPAVQWKLRNIHQMPAIKRAESLDKLEKVLAEWRS

Download         Length: 918 bp

>T213728 NZ_CP109835:3719436-3720014 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
GCCGCTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGACCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGTTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin


Download         Length: 253 a.a.        Molecular weight: 28673.06 Da        Isoelectric Point: 10.1988

>AT213728 WP_223065544.1 NZ_CP081893:c4895904-4895146 [Klebsiella quasipneumoniae]
MSSKLNWLLQNSAPGDVILQSWLSRHAISPSLAFKYTQSGWLKKRGNGVYARAGREPEWNDALACLQNQLAAPVYVAGLS
SLVWQGRSHYLQLKQNQCWLSMENKALLPKWFREFPGVEWIVISGQKLPVLDDKYRVMLDVKGKRLTGSAPELAAYELLS
AVPGTLSFNHAAELFQGLVNLNPRKVEYLLSVSQSVQTKRLYLFFASFYEHGWLRRIDSQKIDLGAGKRQIVVNGKFNAQ
YQITVPERFQKE

Download         Length: 759 bp

>AT213728 NZ_CP109835:3718794-3719348 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References