Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1869278..1869423 Replicon chromosome
Accession NZ_CP081891
Organism Klebsiella pneumoniae strain CT-04

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1869314..1869416 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1869278..1869423 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ663_RS09030 (KZ663_09000) 1864408..1866468 + 2061 WP_004148850.1 oligopeptidase B -
KZ663_RS09035 (KZ663_09005) 1866472..1867131 - 660 WP_002911407.1 exodeoxyribonuclease X -
KZ663_RS09040 (KZ663_09010) 1867210..1867440 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KZ663_RS09045 (KZ663_09015) 1867553..1867927 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KZ663_RS09050 (KZ663_09020) 1867931..1868800 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
KZ663_RS09055 (KZ663_09025) 1868817..1869155 + 339 WP_002911404.1 YebY family protein -
- 1869278..1869423 - 146 - - Antitoxin
- 1869314..1869416 + 103 - - Toxin
KZ663_RS09060 (KZ663_09030) 1869791..1869934 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KZ663_RS09065 (KZ663_09035) 1870039..1871007 - 969 WP_014907334.1 VirK/YbjX family protein -
KZ663_RS09070 (KZ663_09040) 1871164..1871817 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
KZ663_RS09075 (KZ663_09045) 1871814..1872005 - 192 WP_002911395.1 YebW family protein -
KZ663_RS09080 (KZ663_09050) 1872103..1872342 - 240 WP_002911393.1 YebV family protein -
KZ663_RS09085 (KZ663_09055) 1872458..1873891 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213680 NZ_CP081891:1869314-1869416 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213680 NZ_CP081891:c1869423-1869278 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References