Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1834979..1835124 Replicon chromosome
Accession NZ_CP081890
Organism Klebsiella pneumoniae strain IA-021

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1835015..1835117 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1834979..1835124 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ660_RS08855 1830109..1832169 + 2061 WP_004151449.1 oligopeptidase B -
KZ660_RS08860 1832173..1832832 - 660 WP_002911407.1 exodeoxyribonuclease X -
KZ660_RS08865 1832911..1833141 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KZ660_RS08870 1833254..1833628 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KZ660_RS08875 1833632..1834501 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
KZ660_RS08880 1834518..1834856 + 339 WP_004189269.1 YebY family protein -
- 1834979..1835124 - 146 - - Antitoxin
- 1835015..1835117 + 103 - - Toxin
KZ660_RS08885 1835491..1835634 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KZ660_RS08890 1835739..1836707 - 969 WP_004151446.1 VirK/YbjX family protein -
KZ660_RS08895 1836864..1837517 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
KZ660_RS08900 1837514..1837705 - 192 WP_002911395.1 YebW family protein -
KZ660_RS08905 1837803..1838042 - 240 WP_002911393.1 YebV family protein -
KZ660_RS08910 1838158..1839591 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213661 NZ_CP081890:1835015-1835117 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213661 NZ_CP081890:c1835124-1834979 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References