Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1860906..1861051 Replicon chromosome
Accession NZ_CP081889
Organism Klebsiella pneumoniae strain IA-044

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1860942..1861044 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1860906..1861051 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ664_RS09015 (KZ664_09015) 1856036..1858096 + 2061 WP_019705169.1 oligopeptidase B -
KZ664_RS09020 (KZ664_09020) 1858100..1858759 - 660 WP_002911407.1 exodeoxyribonuclease X -
KZ664_RS09025 (KZ664_09025) 1858838..1859068 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KZ664_RS09030 (KZ664_09030) 1859181..1859555 + 375 WP_014343244.1 CopC domain-containing protein YobA -
KZ664_RS09035 (KZ664_09035) 1859559..1860428 + 870 WP_014343243.1 copper homeostasis membrane protein CopD -
KZ664_RS09040 (KZ664_09040) 1860445..1860783 + 339 WP_002911404.1 YebY family protein -
- 1860906..1861051 - 146 - - Antitoxin
- 1860942..1861044 + 103 - - Toxin
KZ664_RS09045 (KZ664_09045) 1861419..1861562 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KZ664_RS09050 (KZ664_09050) 1861667..1862635 - 969 WP_004151446.1 VirK/YbjX family protein -
KZ664_RS09055 (KZ664_09055) 1862792..1863445 + 654 WP_014343242.1 protein-serine/threonine phosphatase -
KZ664_RS09060 (KZ664_09060) 1863442..1863633 - 192 WP_002911395.1 YebW family protein -
KZ664_RS09065 (KZ664_09065) 1863731..1863970 - 240 WP_002911393.1 YebV family protein -
KZ664_RS09070 (KZ664_09070) 1864086..1865519 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213643 NZ_CP081889:1860942-1861044 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213643 NZ_CP081889:c1861051-1860906 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References