Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2754593..2754864 Replicon chromosome
Accession NZ_CP081881
Organism Escherichia coli strain WW2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2754631..2754733 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2754593..2754864 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5O11_RS13110 2751750..2753189 + 1440 WP_024179479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
K5O11_RS13115 2753307..2753543 + 237 WP_001295499.1 YebV family protein -
K5O11_RS13120 2753648..2753839 + 192 WP_001296140.1 YebW family protein -
K5O11_RS13125 2753840..2754496 - 657 WP_000812752.1 protein-serine/threonine phosphatase -
- 2754593..2754864 + 272 - - Antitoxin
- 2754631..2754733 - 103 - - Toxin
K5O11_RS13130 2754892..2755233 - 342 WP_000976484.1 YebY family protein -
K5O11_RS13135 2755246..2756118 - 873 WP_000879323.1 copper homeostasis membrane protein CopD -
K5O11_RS13140 2756122..2756496 - 375 WP_000168737.1 CopC domain-containing protein YobA -
K5O11_RS13145 2756635..2756865 + 231 WP_000916763.1 DNA polymerase III subunit theta -
K5O11_RS13150 2756967..2757623 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
K5O11_RS13155 2757647..2758309 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213612 NZ_CP081881:c2754733-2754631 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT213612 NZ_CP081881:2754593-2754864 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References