Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 5016827..5017460 | Replicon | chromosome |
| Accession | NZ_CP081869 | ||
| Organism | Chenggangzhangella methanolivorans strain CHL1 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | K6K41_RS26465 | Protein ID | WP_261403012.1 |
| Coordinates | 5016827..5017018 (+) | Length | 64 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | K6K41_RS26470 | Protein ID | WP_261403013.1 |
| Coordinates | 5017035..5017460 (+) | Length | 142 a.a. |
Genomic Context
Location: 5012470..5012976 (507 bp)
Type: Others
Protein ID: WP_261403008.1
Type: Others
Protein ID: WP_261403008.1
Location: 5013123..5014349 (1227 bp)
Type: Others
Protein ID: WP_261403009.1
Type: Others
Protein ID: WP_261403009.1
Location: 5014585..5015568 (984 bp)
Type: Others
Protein ID: WP_261403010.1
Type: Others
Protein ID: WP_261403010.1
Location: 5015713..5016765 (1053 bp)
Type: Others
Protein ID: WP_261403011.1
Type: Others
Protein ID: WP_261403011.1
Location: 5016827..5017018 (192 bp)
Type: Toxin
Protein ID: WP_261403012.1
Type: Toxin
Protein ID: WP_261403012.1
Location: 5017035..5017460 (426 bp)
Type: Antitoxin
Protein ID: WP_261403013.1
Type: Antitoxin
Protein ID: WP_261403013.1
Location: 5019938..5020174 (237 bp)
Type: Others
Protein ID: WP_261403014.1
Type: Others
Protein ID: WP_261403014.1
Location: 5017483..5019221 (1739 bp)
Type: Others
Protein ID: Protein_5237
Type: Others
Protein ID: Protein_5237
Location: 5020193..5021413 (1221 bp)
Type: Others
Protein ID: WP_261403015.1
Type: Others
Protein ID: WP_261403015.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6K41_RS26445 (K6K41_25125) | 5012470..5012976 | + | 507 | WP_261403008.1 | hypothetical protein | - |
| K6K41_RS26450 (K6K41_25130) | 5013123..5014349 | + | 1227 | WP_261403009.1 | MFS transporter | - |
| K6K41_RS26455 (K6K41_25135) | 5014585..5015568 | + | 984 | WP_261403010.1 | MDR family oxidoreductase | - |
| K6K41_RS26460 (K6K41_25140) | 5015713..5016765 | + | 1053 | WP_261403011.1 | N-acetyl-gamma-glutamyl-phosphate reductase | - |
| K6K41_RS26465 (K6K41_25145) | 5016827..5017018 | + | 192 | WP_261403012.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| K6K41_RS26470 (K6K41_25150) | 5017035..5017460 | + | 426 | WP_261403013.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| K6K41_RS26475 (K6K41_25155) | 5017483..5019221 | - | 1739 | Protein_5237 | class I poly(R)-hydroxyalkanoic acid synthase | - |
| K6K41_RS26480 (K6K41_25160) | 5019938..5020174 | + | 237 | WP_261403014.1 | hypothetical protein | - |
| K6K41_RS26485 (K6K41_25165) | 5020193..5021413 | - | 1221 | WP_261403015.1 | calcium-binding protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 64 a.a. Molecular weight: 7200.29 Da Isoelectric Point: 11.5249
>T213594 WP_261403012.1 NZ_CP081869:5016827-5017018 [Chenggangzhangella methanolivorans]
VERNSRKLIALLKADGWTPVSQDGSHQTFKHTSNPLLITVPHPRKDLPVGLVRRIYRDAGWRT
VERNSRKLIALLKADGWTPVSQDGSHQTFKHTSNPLLITVPHPRKDLPVGLVRRIYRDAGWRT
Download Length: 192 bp
>T213594 NZ_CP109694:4833850-4834137 [Enterobacter asburiae]
ATGCCAACGGAGTTTGAATGGGATACCAACAAAGCGAAAAGCAATCTCATTAAGCATGGGATCCGCTTTGAAGAAGCTGT
TCTGGTGTTTGACGATCCTTACCATTTATCTTTGCAGGATCGTCATGAAAATGGAGAGTTCCGTTGGCAGACCATTGGCC
TTGTACATGGTCTAATTGTCATTATGGTCGCACACACGGTACGTTTTGAAAGTGGTGACGAAGTCATTCGAATCATTAGC
GCACGAAAGGCGGACCGTAAAGAGAGGAGCCGTTATGAGCATGGTTAA
ATGCCAACGGAGTTTGAATGGGATACCAACAAAGCGAAAAGCAATCTCATTAAGCATGGGATCCGCTTTGAAGAAGCTGT
TCTGGTGTTTGACGATCCTTACCATTTATCTTTGCAGGATCGTCATGAAAATGGAGAGTTCCGTTGGCAGACCATTGGCC
TTGTACATGGTCTAATTGTCATTATGGTCGCACACACGGTACGTTTTGAAAGTGGTGACGAAGTCATTCGAATCATTAGC
GCACGAAAGGCGGACCGTAAAGAGAGGAGCCGTTATGAGCATGGTTAA
Antitoxin
Download Length: 142 a.a. Molecular weight: 14832.71 Da Isoelectric Point: 4.5164
>AT213594 WP_261403013.1 NZ_CP081869:5017035-5017460 [Chenggangzhangella methanolivorans]
MNAKRYFVGVIEKDEDSAFGVWFPDAPGAYGAADEFEDVISAAGRALRHHVEALQTAGMPTPEPRAYDEVINSADVRAAI
AAGAAAIVVPLLADGGRTVRVNVSIERDLVEQIDAAAEARGLTRSAFLAQAARDKILAGVV
MNAKRYFVGVIEKDEDSAFGVWFPDAPGAYGAADEFEDVISAAGRALRHHVEALQTAGMPTPEPRAYDEVINSADVRAAI
AAGAAAIVVPLLADGGRTVRVNVSIERDLVEQIDAAAEARGLTRSAFLAQAARDKILAGVV
Download Length: 426 bp
>AT213594 NZ_CP109694:4834124-4834426 [Enterobacter asburiae]
ATGAGCATGGTTAAACATAAACGCGGTAGTGCGCCTGAGATGAGTGCTCGCCGTGAGGCTGAGCTCAAAGCACTAGCCGA
AAAATCGGAAGCAGAGATTGATTACAGCGATATCCCTGCCATGGAAGATGAACAGTGGTCAGGGGCGGTGCGAGGGAAGT
TCTATCGGCCACTCAAAACTCAGGCGTCTGTACGTATCGACGCTGACGTGATGGAGTGGCTTAAACGGCCTGGAAAAGGT
TACCAGACGAGGCTCAATGCCATTTTGCGTGAAGCTATGCTGCGCGATCAAAACAAAAAATAA
ATGAGCATGGTTAAACATAAACGCGGTAGTGCGCCTGAGATGAGTGCTCGCCGTGAGGCTGAGCTCAAAGCACTAGCCGA
AAAATCGGAAGCAGAGATTGATTACAGCGATATCCCTGCCATGGAAGATGAACAGTGGTCAGGGGCGGTGCGAGGGAAGT
TCTATCGGCCACTCAAAACTCAGGCGTCTGTACGTATCGACGCTGACGTGATGGAGTGGCTTAAACGGCCTGGAAAAGGT
TACCAGACGAGGCTCAATGCCATTTTGCGTGAAGCTATGCTGCGCGATCAAAACAAAAAATAA