Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018334..2018479 Replicon chromosome
Accession NZ_CP081865
Organism Klebsiella pneumoniae strain K5880C

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018370..2018472 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018334..2018479 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J95_RS09810 2013464..2015524 + 2061 WP_004151449.1 oligopeptidase B -
K6J95_RS09815 2015528..2016187 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J95_RS09820 2016266..2016496 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J95_RS09825 2016609..2016983 + 375 WP_039819395.1 CopC domain-containing protein YobA -
K6J95_RS09830 2016987..2017856 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
K6J95_RS09835 2017873..2018211 + 339 WP_002911404.1 YebY family protein -
- 2018334..2018479 - 146 - - Antitoxin
- 2018370..2018472 + 103 - - Toxin
K6J95_RS09840 2018848..2018991 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
K6J95_RS09845 2019096..2020064 - 969 WP_014907334.1 VirK/YbjX family protein -
K6J95_RS09850 2020221..2020874 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
K6J95_RS09855 2020871..2021062 - 192 WP_002911395.1 YebW family protein -
K6J95_RS09860 2021160..2021399 - 240 WP_002911393.1 YebV family protein -
K6J95_RS09865 2021515..2022948 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213579 NZ_CP081865:2018370-2018472 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213579 NZ_CP081865:c2018479-2018334 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References