Detailed information of TA system TA213572

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-YafN
• Location: 3347655..3348177
• Replicon: chromosome
• Accession: NZ_CP081864
• Organism: Symbiopectobacterium purcellii strain SyEd1

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: K6K13_RS15665
• Protein ID: WP_222157824.1
• Coordinates: 3347893..3348177 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: K6K13_RS15660
• Protein ID: WP_222157823.1
• Coordinates: 3347655..3347903 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K6K13_RS15645 (K6K13_15645)	3344282..3345793	-	1512	WP_222157820.1	dGTPase	-
K6K13_RS15650 (K6K13_15650)	3345923..3346624	+	702	WP_222157821.1	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	-
K6K13_RS15655 (K6K13_15655)	3346624..3347445	+	822	WP_222157822.1	vitamin B12 ABC transporter substrate-binding protein BtuF	-
K6K13_RS15660 (K6K13_15660)	3347655..3347903	+	249	WP_222157823.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
K6K13_RS15665 (K6K13_15665)	3347893..3348177	+	285	WP_222157824.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K6K13_RS15670 (K6K13_15670)	3348500..3348757	+	258	WP_222157825.1	hypothetical protein	-
K6K13_RS15675 (K6K13_15675)	3348843..3349190	-	348	WP_222157826.1	iron-sulfur cluster insertion protein ErpA	-
K6K13_RS15680 (K6K13_15680)	3349283..3350677	-	1395	WP_222161128.1	H(+)/Cl(-) exchange transporter ClcA	-
K6K13_RS15685 (K6K13_15685)	3350838..3352118	+	1281	WP_222157827.1	glutamate-1-semialdehyde 2,1-aminomutase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10956.62 Da
• Isoelectric Point: 10.6761

>T213572 WP_222157824.1 NZ_CP081864:3347893-3348177 [Symbiopectobacterium purcellii]
MTYKLAFNESALKEWKKLGHTLRDQFKKKLIERLQNPRVPASQLHGRKDQFKIKLRGAGYRLVYSVNDDIVTVTVIGVGK
RENDDIYTATQHRN

Nucleotide

• Length: 285 bp

>T213572 NZ_CP109692:2339800-2340087 [Enterobacter asburiae]
ATGCATAAATTAACACCCTACGATCCAGCCAATGCGCTGGTGGATGACGAGGAAATCGCCGTGTTTATGGCTGATGCCTT
AGAAACGGGCGATTCAGCGTATATTGCTAAAGCTCTGGGCGTCATCGCGCGAGCGAAAGGAATGTCGACCATTTCACAGC
AAACTGGCCTATCACGAGAGCAACTGTATCGATCGTTCAGTGATAAAGGAAACCCAACGCTTAAAACCACTCTGGCGGTC
ATGAAAGCATTGGGTCTTGGGCTAACAATCAAACACGCTGGAGATTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8966.22 Da
• Isoelectric Point: 3.8209

>AT213572 WP_222157823.1 NZ_CP081864:3347655-3347903 [Symbiopectobacterium purcellii]
MAFQILTTTAASITELKRDPMGTFNAGEGAPVAILNRNEPAFYCVPPALYAQLMEILEDQELGRIADERIGEAVIEVNID
DL

Nucleotide

• Length: 249 bp

>AT213572 NZ_CP109692:2339495-2339797 [Enterobacter asburiae]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCAACGCTGGGAGCAAAACTTAAAAGATCGGCGAGCGAAAACCATTATCGC
TTCCCGCCTCTTTCGGTTGGCAAATGGTTTAGCGGGCGACATTAAACCCGTGGGCGAAGGTATAAGTGAGCTGAGGATCC
ACTATGGTCCGGGCTACAGAATCTATTTTAAAGACCAGGGCAATTGCATCATCGTGCTGTTGTGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATCCCAATGGCAGGAGTGAATGA