Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 2836650..2837375 Replicon chromosome
Accession NZ_CP081864
Organism Symbiopectobacterium purcellii strain SyEd1

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag K6K13_RS13390 Protein ID WP_222157469.1
Coordinates 2836650..2836970 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag K6K13_RS13395 Protein ID WP_222157470.1
Coordinates 2837040..2837375 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K13_RS13350 (K6K13_13350) 2831991..2832335 + 345 WP_222157464.1 GPW/gp25 family protein -
K6K13_RS13355 (K6K13_13355) 2832340..2832593 + 254 Protein_2626 baseplate assembly protein -
K6K13_RS13360 (K6K13_13360) 2832560..2833011 + 452 Protein_2627 contractile injection system protein, VgrG/Pvc8 family -
K6K13_RS13365 (K6K13_13365) 2833049..2833295 + 247 Protein_2628 ogr/Delta-like zinc finger family protein -
K6K13_RS13370 (K6K13_13370) 2833545..2834507 + 963 WP_222157466.1 hypothetical protein -
K6K13_RS13375 (K6K13_13375) 2834946..2835374 - 429 WP_222157467.1 tRNA(fMet)-specific endonuclease VapC -
K6K13_RS13380 (K6K13_13380) 2835374..2835604 - 231 WP_039360473.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
K6K13_RS13385 (K6K13_13385) 2835699..2836532 - 834 WP_222157468.1 DUF4942 domain-containing protein -
K6K13_RS13390 (K6K13_13390) 2836650..2836970 - 321 WP_222157469.1 TA system toxin CbtA family protein Toxin
K6K13_RS13395 (K6K13_13395) 2837040..2837375 - 336 WP_222157470.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
K6K13_RS13400 (K6K13_13400) 2837415..2837888 - 474 WP_222157471.1 DNA repair protein RadC -
K6K13_RS13405 (K6K13_13405) 2837940..2838761 - 822 WP_222157472.1 DUF932 domain-containing protein -
K6K13_RS13410 (K6K13_13410) 2838843..2839055 - 213 WP_222157473.1 hypothetical protein -
K6K13_RS13415 (K6K13_13415) 2839237..2839494 - 258 WP_222157474.1 hypothetical protein -
K6K13_RS13420 (K6K13_13420) 2839537..2839902 - 366 WP_222157475.1 hypothetical protein -
K6K13_RS13425 (K6K13_13425) 2840000..2840677 - 678 WP_222157476.1 WYL domain-containing protein -
K6K13_RS13430 (K6K13_13430) 2840732..2840947 - 216 WP_252120284.1 ubiquinol-cytochrome C chaperone family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(8-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12087.72 Da        Isoelectric Point: 5.0890

>T213571 WP_222157469.1 NZ_CP081864:c2836970-2836650 [Symbiopectobacterium purcellii]
MQTSPAIPSREDQSCPSPVAVWQRLLAYLLEKHYGLTLNDTPFCEENVIQEHIDAGVTLVNAVNFLVERYELVRIDRNGF
NWQEQSPFLSAVDVLRARRTTGLLKS

Download         Length: 321 bp

>T213571 NZ_CP109692:2339495-2339797 [Enterobacter asburiae]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCAACGCTGGGAGCAAAACTTAAAAGATCGGCGAGCGAAAACCATTATCGC
TTCCCGCCTCTTTCGGTTGGCAAATGGTTTAGCGGGCGACATTAAACCCGTGGGCGAAGGTATAAGTGAGCTGAGGATCC
ACTATGGTCCGGGCTACAGAATCTATTTTAAAGACCAGGGCAATTGCATCATCGTGCTGTTGTGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATCCCAATGGCAGGAGTGAATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12474.02 Da        Isoelectric Point: 5.5507

>AT213571 WP_222157470.1 NZ_CP081864:c2837375-2837040 [Symbiopectobacterium purcellii]
MPSSDTLEWGLKRAITPQFGARLVQEGHYLHYLADRASVVGTFSETEARHLEQSFPELIKQLEQKLRTGELNPRQQGCIT
LHCNEWTCEADTLGSFGYVYIAIYPSSAAAQ

Download         Length: 336 bp

>AT213571 NZ_CP109692:2339800-2340087 [Enterobacter asburiae]
ATGCATAAATTAACACCCTACGATCCAGCCAATGCGCTGGTGGATGACGAGGAAATCGCCGTGTTTATGGCTGATGCCTT
AGAAACGGGCGATTCAGCGTATATTGCTAAAGCTCTGGGCGTCATCGCGCGAGCGAAAGGAATGTCGACCATTTCACAGC
AAACTGGCCTATCACGAGAGCAACTGTATCGATCGTTCAGTGATAAAGGAAACCCAACGCTTAAAACCACTCTGGCGGTC
ATGAAAGCATTGGGTCTTGGGCTAACAATCAAACACGCTGGAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References