Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 2834946..2835604 | Replicon | chromosome |
| Accession | NZ_CP081864 | ||
| Organism | Symbiopectobacterium purcellii strain SyEd1 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | K6K13_RS13375 | Protein ID | WP_222157467.1 |
| Coordinates | 2834946..2835374 (-) | Length | 143 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A0A1V2R781 |
| Locus tag | K6K13_RS13380 | Protein ID | WP_039360473.1 |
| Coordinates | 2835374..2835604 (-) | Length | 77 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6K13_RS13335 (K6K13_13335) | 2829986..2830360 | - | 375 | WP_222157463.1 | DUF6232 family protein | - |
| K6K13_RS13345 (K6K13_13345) | 2831359..2831994 | + | 636 | Protein_2624 | phage baseplate assembly protein V | - |
| K6K13_RS13350 (K6K13_13350) | 2831991..2832335 | + | 345 | WP_222157464.1 | GPW/gp25 family protein | - |
| K6K13_RS13355 (K6K13_13355) | 2832340..2832593 | + | 254 | Protein_2626 | baseplate assembly protein | - |
| K6K13_RS13360 (K6K13_13360) | 2832560..2833011 | + | 452 | Protein_2627 | contractile injection system protein, VgrG/Pvc8 family | - |
| K6K13_RS13365 (K6K13_13365) | 2833049..2833295 | + | 247 | Protein_2628 | ogr/Delta-like zinc finger family protein | - |
| K6K13_RS13370 (K6K13_13370) | 2833545..2834507 | + | 963 | WP_222157466.1 | hypothetical protein | - |
| K6K13_RS13375 (K6K13_13375) | 2834946..2835374 | - | 429 | WP_222157467.1 | tRNA(fMet)-specific endonuclease VapC | Toxin |
| K6K13_RS13380 (K6K13_13380) | 2835374..2835604 | - | 231 | WP_039360473.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| K6K13_RS13385 (K6K13_13385) | 2835699..2836532 | - | 834 | WP_222157468.1 | DUF4942 domain-containing protein | - |
| K6K13_RS13390 (K6K13_13390) | 2836650..2836970 | - | 321 | WP_222157469.1 | TA system toxin CbtA family protein | - |
| K6K13_RS13395 (K6K13_13395) | 2837040..2837375 | - | 336 | WP_222157470.1 | type IV toxin-antitoxin system YeeU family antitoxin | - |
| K6K13_RS13400 (K6K13_13400) | 2837415..2837888 | - | 474 | WP_222157471.1 | DNA repair protein RadC | - |
| K6K13_RS13405 (K6K13_13405) | 2837940..2838761 | - | 822 | WP_222157472.1 | DUF932 domain-containing protein | - |
| K6K13_RS13410 (K6K13_13410) | 2838843..2839055 | - | 213 | WP_222157473.1 | hypothetical protein | - |
| K6K13_RS13415 (K6K13_13415) | 2839237..2839494 | - | 258 | WP_222157474.1 | hypothetical protein | - |
| K6K13_RS13420 (K6K13_13420) | 2839537..2839902 | - | 366 | WP_222157475.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 143 a.a. Molecular weight: 15759.00 Da Isoelectric Point: 6.7190
>T213570 WP_222157467.1 NZ_CP081864:c2835374-2834946 [Symbiopectobacterium purcellii]
MLKYLLDTNICIYTIKNKPQEVRDAFYRHYGQFAISAITLMELIYGAEKSVNPEKNLAVIEGFSARLEVQTYGFDAAVHT
GQIRAELAKQGTPIGPYDAMLAGHARSAGLILITNNVREFERVPGLRVENWVGSSADNSQPL
MLKYLLDTNICIYTIKNKPQEVRDAFYRHYGQFAISAITLMELIYGAEKSVNPEKNLAVIEGFSARLEVQTYGFDAAVHT
GQIRAELAKQGTPIGPYDAMLAGHARSAGLILITNNVREFERVPGLRVENWVGSSADNSQPL
Download Length: 429 bp
>T213570 NZ_CP109692:c2087566-2087282 [Enterobacter asburiae]
ATGACTTATGAACTGGCATTTGACCCGAGGGCGTTAAAGGAGTGGAGCAAGCTGGGGCAGACTGTAAAAGACCAGTTTAA
GAAGAAACTTGCGGACGTGCTGGTGAGCCCCAGGGTCGAATCGGCCCGCCTGCATGGTCTGCCGGATTGCTACAAAATAA
AACTCAGATCGCAGGGTTATCGTTTGGTCTATCAGGTTCAGGACAACGTTGTAACGGTATTCGTTATCGCTATCGGTAAG
CGAGAGAAATCAGCCGTTTATCATGATGCAAACAAACGGCTCTAA
ATGACTTATGAACTGGCATTTGACCCGAGGGCGTTAAAGGAGTGGAGCAAGCTGGGGCAGACTGTAAAAGACCAGTTTAA
GAAGAAACTTGCGGACGTGCTGGTGAGCCCCAGGGTCGAATCGGCCCGCCTGCATGGTCTGCCGGATTGCTACAAAATAA
AACTCAGATCGCAGGGTTATCGTTTGGTCTATCAGGTTCAGGACAACGTTGTAACGGTATTCGTTATCGCTATCGGTAAG
CGAGAGAAATCAGCCGTTTATCATGATGCAAACAAACGGCTCTAA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8707.79 Da Isoelectric Point: 4.4091
>AT213570 WP_039360473.1 NZ_CP081864:c2835604-2835374 [Symbiopectobacterium purcellii]
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEEQGVTPDFMITREQPDDQIREDF
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEEQGVTPDFMITREQPDDQIREDF
Download Length: 231 bp
>AT213570 NZ_CP109692:c2087798-2087556 [Enterobacter asburiae]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAACGAGGCTTATGCCGTGCTGGAAAAACTCAATATCACCCC
AACGGAAGCCGTGCGATTACTGTTTCAGTACGTCGCGGAGACGGGACGTATGCCGGTGAAAACGGTCACGATTAGCGACA
GCGAAGATGCGCTGATACAGACGGTCCGGGAGCGACTGGCGAATCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAACGAGGCTTATGCCGTGCTGGAAAAACTCAATATCACCCC
AACGGAAGCCGTGCGATTACTGTTTCAGTACGTCGCGGAGACGGGACGTATGCCGGTGAAAACGGTCACGATTAGCGACA
GCGAAGATGCGCTGATACAGACGGTCCGGGAGCGACTGGCGAATCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|