Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1201763..1202397 Replicon chromosome
Accession NZ_CP081864
Organism Symbiopectobacterium purcellii strain SyEd1

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag K6K13_RS05650 Protein ID WP_222159900.1
Coordinates 1201763..1201966 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag K6K13_RS05655 Protein ID WP_222159901.1
Coordinates 1202029..1202397 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K13_RS05620 (K6K13_05620) 1197247..1197585 + 339 WP_195315229.1 P-II family nitrogen regulator -
K6K13_RS05625 (K6K13_05625) 1197619..1198911 + 1293 WP_222159896.1 ammonium transporter AmtB -
K6K13_RS05630 (K6K13_05630) 1198989..1199855 - 867 WP_222159897.1 acyl-CoA thioesterase II -
K6K13_RS05635 (K6K13_05635) 1200113..1200628 + 516 WP_222159898.1 YbaY family lipoprotein -
K6K13_RS05640 (K6K13_05640) 1200642..1200959 - 318 WP_222159899.1 MGMT family protein -
K6K13_RS05650 (K6K13_05650) 1201763..1201966 - 204 WP_222159900.1 HHA domain-containing protein Toxin
K6K13_RS05655 (K6K13_05655) 1202029..1202397 - 369 WP_222159901.1 Hha toxicity modulator TomB Antitoxin
K6K13_RS05660 (K6K13_05660) 1202895..1203035 - 141 WP_195315222.1 type B 50S ribosomal protein L36 -
K6K13_RS05665 (K6K13_05665) 1203066..1203314 - 249 WP_222159902.1 type B 50S ribosomal protein L31 -
K6K13_RS05670 (K6K13_05670) 1203478..1206624 - 3147 WP_222159903.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-117)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8105.50 Da        Isoelectric Point: 9.3935

>T213568 WP_222159900.1 NZ_CP081864:c1201966-1201763 [Symbiopectobacterium purcellii]
MKKIDYLMRLRKCTTIDTLERVIEKNKYQLSSDELEMFYSAADHRLAELTMNKIYDKVPTAVWKYVR

Download         Length: 204 bp

>T213568 NZ_CP109692:1534457-1534675 [Enterobacter asburiae]
ATGTCTGATAAACCACTCACAAAAATCGATTATTTGATGCGCTTACGGCGTTGTCAGTCAATTGACACGCTTGAGCGCGT
CATTGAAAAGAATAAATACGAGCTTTCTGATAATGAACTGGCGGTATTTTATTCAGCCGCTGACCATCGTCTTGCTGAAC
TGACAATGAATAAACTGTATGACAAAATCCCTACTTCTGTGTGGAAATTTGTCCGTTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13978.64 Da        Isoelectric Point: 4.4431

>AT213568 WP_222159901.1 NZ_CP081864:c1202397-1202029 [Symbiopectobacterium purcellii]
MDEYSPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNYPTSAINLQLNELIEHIATFILTFKIKYPDEDELSKRVEQYL
DDTYALFSNYGINGAELQRWQRSKAALLGMFSQENVCSSAKS

Download         Length: 369 bp

>AT213568 NZ_CP109692:1534055-1534429 [Enterobacter asburiae]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGATGAAAGTAACCATGGCTGGGTAAACGACCCAACATCTGCCATCAATTTACAGTTGAATGAGCTGATAGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGCTCATTGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGTTACGGCATTAACGCGCAGGATTTGCAAAAATGGCGTAAATCGGGAAATCGGCT
ATTCCGCTGTTTCGTCAACGTGAGCAGAGCTAACCCGGTGAGTCTTTCCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References