Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 726567..727245 Replicon chromosome
Accession NZ_CP081864
Organism Symbiopectobacterium purcellii strain SyEd1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag K6K13_RS03555 Protein ID WP_222159563.1
Coordinates 726814..727245 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag K6K13_RS03550 Protein ID WP_222159562.1
Coordinates 726567..726833 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K13_RS03530 (K6K13_03530) 721918..722526 - 609 WP_222159559.1 HD domain-containing protein -
K6K13_RS03535 (K6K13_03535) 722964..724474 + 1511 Protein_690 alpha/beta hydrolase -
K6K13_RS03540 (K6K13_03540) 724598..725245 + 648 WP_222159560.1 hemolysin III family protein -
K6K13_RS03545 (K6K13_03545) 725307..726308 - 1002 WP_222159561.1 tRNA-modifying protein YgfZ -
K6K13_RS03550 (K6K13_03550) 726567..726833 + 267 WP_222159562.1 FAD assembly factor SdhE Antitoxin
K6K13_RS03555 (K6K13_03555) 726814..727245 + 432 WP_222159563.1 protein YgfX Toxin
K6K13_RS03560 (K6K13_03560) 727294..727812 - 519 WP_222160951.1 flavodoxin FldB -
K6K13_RS03565 (K6K13_03565) 728222..729547 - 1326 WP_222159564.1 MFS transporter -
K6K13_RS03570 (K6K13_03570) 729866..730765 + 900 WP_222159565.1 site-specific tyrosine recombinase XerD -
K6K13_RS03575 (K6K13_03575) 730844..731560 + 717 WP_222159566.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 17103.13 Da        Isoelectric Point: 11.7434

>T213566 WP_222159563.1 NZ_CP081864:726814-727245 [Symbiopectobacterium purcellii]
VALWRCDLRVSWRMQVFSLLVHGPLLLLILLAPWPDGYAVLWLSLMTLVVFGFIRSQRNIKARHGEIVLQAEANLEWQHH
RWRIIRRPWMLKNGILLSLRRSDGKRRQRLWLASDNMDKQEWRHLRQLLLENKAWAGENPDAQ

Download         Length: 432 bp

>T213566 NZ_CP109691:46643-46927 [Enterobacter asburiae]
GTGTATAAACTCACCGAACGGGCAGCAGACGACTTCGCCGGGATTTATGACTATACGCTCTTGAAATTTGGTGAAGCTCA
GGCAGATCATTATACAGACGCACTTGAGGCATTTTTCGAGACACTTGCCGGAATGCCAGATATGGGACGTGACTACCATG
CCGTTTCTGGTGTGATGCGCATTGAATTTCAGCGACACGCCATTTTTTATACGGTTCGTGATACGGATATTCTGATTGCA
CGTATTTTGCACCAACAGATGAACCATAAACGCCATTTACTGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10455.91 Da        Isoelectric Point: 4.8727

>AT213566 WP_222159562.1 NZ_CP081864:726567-726833 [Symbiopectobacterium purcellii]
MDIDNKARIHWACRRGMRELDIAIMPFFEHEYDVLNDDDKRAFVRLLQCDDPDLFNWLMNHGEPEDGEPKRMISLIQTRN
KDRGPVAL

Download         Length: 267 bp

>AT213566 NZ_CP109691:46408-46650 [Enterobacter asburiae]
ATGGCCAGAACAACAAGCGTTACGATTGGCGAACAACTCGATTCGTTTATCAGTCGATTAATAGACAGTGGCCGTTATGG
CTCTGCGAGTGAAGTTATGCGTTCTGCTCTGCGATTACTGGAGCAACAGGAAACAAATGATGAAGTTGTTCGCCAGGCAG
TAATTACCGGGCTGGAAAGCGGTGAAAGCTCGCTATCACTGCGGGATATTGCAGAAAAAAGAAAGCTGAGACATCGTGTA
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References