Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 201914..202474 Replicon chromosome
Accession NZ_CP081832
Organism Idiomarina abyssalis strain MSP-CT

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K5X84_RS00960 Protein ID WP_199494489.1
Coordinates 201914..202192 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K5X84_RS00965 Protein ID WP_199494488.1
Coordinates 202202..202474 (-) Length 91 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5X84_RS00945 (K5X84_00945) 198796..200802 - 2007 WP_222236280.1 DNA helicase Rep -
K5X84_RS00950 (K5X84_00950) 200913..201158 + 246 WP_011233471.1 accessory factor UbiK family protein -
K5X84_RS00955 (K5X84_00955) 201168..201908 + 741 WP_222236282.1 ferredoxin--NADP reductase -
K5X84_RS00960 (K5X84_00960) 201914..202192 - 279 WP_199494489.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K5X84_RS00965 (K5X84_00965) 202202..202474 - 273 WP_199494488.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
K5X84_RS00970 (K5X84_00970) 202585..203316 - 732 WP_222236284.1 DsbA family protein -
K5X84_RS00975 (K5X84_00975) 203331..203855 - 525 WP_222236286.1 protein disulfide oxidoreductase -
K5X84_RS00980 (K5X84_00980) 203845..205929 - 2085 WP_222236288.1 protein-disulfide reductase DsbD family protein -
K5X84_RS00985 (K5X84_00985) 205979..206359 - 381 WP_222236290.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 11003.76 Da        Isoelectric Point: 4.8228

>T213538 WP_199494489.1 NZ_CP081832:c202192-201914 [Idiomarina abyssalis]
MIYWEEDALKDRERIFEFLYNFNPIVAEQTDSLIQSKVETLLEQPYIGVKRENIKGRLLILPDISMLVPYYIDGTNIRVL
RVLHEKQQFPFT

Download         Length: 279 bp

>T213538 NZ_CP109614:1450262-1450678 [Klebsiella sp. KP20-425-1]
ATGAAGAAAACCTGGATGCTCGACACTAACATCTGCTCGTTCATTATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGTGATCGCATCGTGGTCTCGGCCGTGACGTATGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCCATCCTGCCCTGGGACCGGGCC
GCGGTGGACGCCACGACCGACATCCGGGTGGCGCTGCACCTCGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGCCACGCCATCGCGGCGGGCGCCGTCCTGGTGACGAACAATGTGAGAGAGTTTGCGCGGGTGCCTGGACTGACACTGG
AAGACTGGGTTATTTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10651.84 Da        Isoelectric Point: 8.0223

>AT213538 WP_199494488.1 NZ_CP081832:c202474-202202 [Idiomarina abyssalis]
METRIQFRIDEQTKHLAQQQAESEGRTLSDACRQLAEQLASERRKQLSQNSWLTEQVNQAFQKLESGQSEFMDNEQAKSR
MEKFKAQFRK

Download         Length: 273 bp

>AT213538 NZ_CP109614:1450035-1450265 [Klebsiella sp. KP20-425-1]
ATGCGCACAGTTTCGATATTTAAAAACGGCAATAACCGCGCCATCCGTCTGCCCCGGGACCTGGATTTTGACGGCGTCAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGCTGG
ACAGGGCCGATCCGGACTTTATGGCGGAACGTGAGGATGTGGTCAGCGATGAAGGACGCTTTGAGCCATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References