Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013367..2013512 Replicon chromosome
Accession NZ_CP081820
Organism Klebsiella pneumoniae strain F726925

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013403..2013505 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013367..2013512 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5O13_RS09860 (K5O13_09860) 2008497..2010557 + 2061 WP_004151449.1 oligopeptidase B -
K5O13_RS09865 (K5O13_09865) 2010561..2011220 - 660 WP_002911407.1 exodeoxyribonuclease X -
K5O13_RS09870 (K5O13_09870) 2011299..2011529 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K5O13_RS09875 (K5O13_09875) 2011642..2012016 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K5O13_RS09880 (K5O13_09880) 2012020..2012889 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K5O13_RS09885 (K5O13_09885) 2012906..2013244 + 339 WP_002911404.1 YebY family protein -
- 2013367..2013512 - 146 - - Antitoxin
- 2013403..2013505 + 103 - - Toxin
K5O13_RS09890 (K5O13_09890) 2013880..2014023 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K5O13_RS09895 (K5O13_09895) 2014128..2015096 - 969 WP_004151446.1 VirK/YbjX family protein -
K5O13_RS09900 (K5O13_09900) 2015253..2015906 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K5O13_RS09905 (K5O13_09905) 2015903..2016094 - 192 WP_002911395.1 YebW family protein -
K5O13_RS09910 (K5O13_09910) 2016192..2016431 - 240 WP_002911393.1 YebV family protein -
K5O13_RS09915 (K5O13_09915) 2016547..2017980 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T213494 NZ_CP081820:2013403-2013505 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT213494 NZ_CP081820:c2013512-2013367 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References