Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2019896..2020167 | Replicon | chromosome |
| Accession | NZ_CP081813 | ||
| Organism | Shigella flexneri strain WW1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2020026..2020129 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2019896..2020167 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5O10_RS09715 | 2016451..2017113 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| K5O10_RS09720 | 2017137..2017793 | - | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| K5O10_RS09725 | 2017895..2018125 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| K5O10_RS09730 | 2018264..2018638 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| K5O10_RS09735 | 2018642..2019514 | + | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| K5O10_RS09740 | 2019527..2019868 | + | 342 | WP_000976492.1 | YebY family protein | - |
| - | 2019896..2020167 | - | 272 | - | - | Antitoxin |
| - | 2020026..2020129 | + | 104 | - | - | Toxin |
| K5O10_RS09745 | 2020264..2020920 | + | 657 | WP_000812724.1 | protein-serine/threonine phosphatase | - |
| K5O10_RS09750 | 2020921..2021112 | - | 192 | WP_001296140.1 | YebW family protein | - |
| K5O10_RS09755 | 2021217..2021453 | - | 237 | WP_001295499.1 | YebV family protein | - |
| K5O10_RS09760 | 2021571..2023010 | - | 1440 | WP_000057022.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T213455 NZ_CP081813:2020026-2020129 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT213455 NZ_CP081813:c2020167-2019896 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
