Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1145616..1145849 Replicon chromosome
Accession NC_007613
Organism Shigella boydii Sb227

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1145617..1145720 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1145616..1145849 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBO_RS06310 1140677..1141138 + 462 WP_000201268.1 hypothetical protein -
SBO_RS06315 1141135..1141341 + 207 WP_000979502.1 helix-turn-helix domain-containing protein -
SBO_RS06320 1141690..1141947 + 258 WP_000288814.1 antitoxin -
SBO_RS06325 1141948..1142265 + 318 WP_000373726.1 type II toxin-antitoxin system PemK/MazF family toxin -
SBO_RS30380 1142425..1142571 - 147 WP_000285696.1 hypothetical protein -
SBO_RS06330 1143130..1143534 + 405 Protein_1134 DNA-binding protein -
SBO_RS06340 1143587..1144800 + 1214 WP_134810244.1 IS3 family transposase -
SBO_RS06345 1144968..1145495 + 528 Protein_1136 tyrosine-type recombinase/integrase -
- 1145616..1145849 + 234 - - Antitoxin
- 1145617..1145720 - 104 - - Toxin
SBO_RS06355 1145877..1146218 - 342 WP_000976476.1 YebY family protein -
SBO_RS06360 1146231..1147098 - 868 Protein_1138 copper homeostasis membrane protein CopD -
SBO_RS06365 1147102..1147476 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SBO_RS06370 1147615..1147845 + 231 WP_000916761.1 DNA polymerase III subunit theta -
SBO_RS06375 1147947..1148603 + 657 WP_000011642.1 carbon-nitrogen hydrolase family protein -
SBO_RS06380 1148627..1149289 + 663 WP_000944260.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1136751..1209537 72786
- inside IScluster/Tn - - 1143587..1152915 9328


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T21342 NC_007613:c1145720-1145617 [Shigella boydii Sb227]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 234 bp

>AT21342 NC_007613:1145616-1145849 [Shigella boydii Sb227]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References