Detailed information of TA system TA213337

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yfjZ-ypjF/CbtA-CbeA
• Location: 1231632..1232302
• Replicon: chromosome
• Accession: NZ_CP081767
• Organism: Escherichia coli strain 0H18

Toxin (Protein)

• Gene name: ypjF
• Uniprot ID: -
• Locus tag: J6O59_RS06100
• Protein ID: WP_016243791.1
• Coordinates: 1231632..1231961 (-)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: J6O59_RS06105
• Protein ID: WP_016243790.1
• Coordinates: 1231982..1232302 (-)
• Length: 107 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J6O59_RS06080 (1226686)	1226686..1227270	+	585	WP_016243792.1	tail fiber assembly protein	-
J6O59_RS06085 (1227340)	1227340..1228113	-	774	WP_000355482.1	hypothetical protein	-
J6O59_RS06090 (1228520)	1228520..1229953	+	1434	WP_001288444.1	DNA cytosine methyltransferase	-
J6O59_RS06095 (1229988)	1229988..1231202	-	1215	WP_012602456.1	type II restriction endonuclease	-
J6O59_RS06100 (1231632)	1231632..1231961	-	330	WP_016243791.1	TA system toxin CbtA family protein	Toxin
J6O59_RS06105 (1231982)	1231982..1232302	-	321	WP_016243790.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
J6O59_RS06110 (1232320)	1232320..1232541	-	222	WP_016243789.1	DUF987 domain-containing protein	-
J6O59_RS06115 (1232550)	1232550..1233032	-	483	WP_016243788.1	DNA repair protein RadC	-
J6O59_RS06120 (1233041)	1233041..1233499	-	459	WP_016243787.1	antirestriction protein	-
J6O59_RS06125 (1233662)	1233662..1233753	-	92	Protein_1198	DUF905 domain-containing protein	-
J6O59_RS06130 (1233987)	1233987..1234723	+	737	Protein_1199	IS3 family transposase	-
J6O59_RS06135 (1235396)	1235396..1236904	+	1509	WP_001189123.1	group II intron reverse transcriptase/maturase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1187568..1269525	81957

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-107)

Antitoxin

• Antitoxin CbeA (6-105)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 12312.37 Da
• Isoelectric Point: 9.5496

>T213337 WP_016243791.1 NZ_CP081767:c1231961-1231632 [Escherichia coli]
MKTLPATISRAAKPCLTPVAAWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGITLADAVNFLVDKYELVRIDRKGF
SWQEQTPYLSVVDILRARRSTGLLKAKVK

Nucleotide

• Length: 330 bp

>T213337 NZ_CP107556:c1219034-1218288 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTAGTAGGCGCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGGAGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCGGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin

Protein

• Length: 107 a.a.
• Molecular weight: 11874.45 Da
• Isoelectric Point: 7.3231

>AT213337 WP_016243790.1 NZ_CP081767:c1232302-1231982 [Escherichia coli]
MRSNATWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECLKLDAAFPHFISQMESMLTTGEMNSRHAHCAILY
HNGFTCEADTLGSCGYVYIAIYSTQR

Nucleotide

• Length: 321 bp

>AT213337 NZ_CP107556:c1218287-1218117 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA