Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | chpSB/PRK09812-ChpS |
| Location | 4328418..4329013 | Replicon | chromosome |
| Accession | NZ_CP081762 | ||
| Organism | Escherichia coli strain CX21 | ||
Toxin (Protein)
| Gene name | chpB | Uniprot ID | V0SXT4 |
| Locus tag | J6O46_RS21275 | Protein ID | WP_000239581.1 |
| Coordinates | 4328418..4328768 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | chpS | Uniprot ID | L4JJX7 |
| Locus tag | J6O46_RS21280 | Protein ID | WP_001223213.1 |
| Coordinates | 4328762..4329013 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J6O46_RS21255 (4323867) | 4323867..4324889 | - | 1023 | WP_001548970.1 | ABC transporter permease | - |
| J6O46_RS21260 (4324903) | 4324903..4326405 | - | 1503 | WP_001095667.1 | sugar ABC transporter ATP-binding protein | - |
| J6O46_RS21265 (4326543) | 4326543..4327499 | - | 957 | WP_000265933.1 | galactofuranose ABC transporter substrate-binding protein YtfQ | - |
| J6O46_RS21270 (4327809) | 4327809..4328339 | + | 531 | WP_000055072.1 | inorganic diphosphatase | - |
| J6O46_RS21275 (4328418) | 4328418..4328768 | - | 351 | WP_000239581.1 | endoribonuclease toxin ChpB | Toxin |
| J6O46_RS21280 (4328762) | 4328762..4329013 | - | 252 | WP_001223213.1 | type II toxin-antitoxin system antitoxin ChpS | Antitoxin |
| J6O46_RS21285 (4329225) | 4329225..4329566 | - | 342 | WP_001219160.1 | gamma-glutamylcyclotransferase | - |
| J6O46_RS21290 (4329569) | 4329569..4333348 | - | 3780 | WP_001548968.1 | autotransporter assembly complex protein TamB | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12453.41 Da Isoelectric Point: 6.2206
>T213323 WP_000239581.1 NZ_CP081762:c4328768-4328418 [Escherichia coli]
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAAGEVVEEALLRLQAVVE
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAAGEVVEEALLRLQAVVE
Download Length: 351 bp
>T213323 NZ_CP107532:2742891-2743229 [Methylobacterium sp. FF17]
ATGCAGATCCGTTTCCGGTCTAGGCGCCTGGGGAAGGCGCTGTCGGACCCGAAGGAGATGGCGAAGGCCTACGGGGACAG
GGCGAAACCGATACGGAAGCGGCTGGACGTGTTGGGGCAGGCGGCCTGCCTCTCGGACGTTCCGACGGAGCCACCCGTCC
GCCGGCATCAACTCGGCGGTAACCGGGACGGCCAACTCTCGGTCACGATCAAGGACAACTGGCGTATCGTCTTCGTGCCC
GACCACGACCCGGTGCCCTGCCTGCCTGACGGCGGGCTCGACACGGGTCAGGTCACGGCGGTCGAGATCATCGAAATCGT
CGACTACCATGGCAACTGA
ATGCAGATCCGTTTCCGGTCTAGGCGCCTGGGGAAGGCGCTGTCGGACCCGAAGGAGATGGCGAAGGCCTACGGGGACAG
GGCGAAACCGATACGGAAGCGGCTGGACGTGTTGGGGCAGGCGGCCTGCCTCTCGGACGTTCCGACGGAGCCACCCGTCC
GCCGGCATCAACTCGGCGGTAACCGGGACGGCCAACTCTCGGTCACGATCAAGGACAACTGGCGTATCGTCTTCGTGCCC
GACCACGACCCGGTGCCCTGCCTGCCTGACGGCGGGCTCGACACGGGTCAGGTCACGGCGGTCGAGATCATCGAAATCGT
CGACTACCATGGCAACTGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9331.64 Da Isoelectric Point: 4.6509
>AT213323 WP_001223213.1 NZ_CP081762:c4329013-4328762 [Escherichia coli]
MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNATELSEQDVWGKSTPAGD
EIW
MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNATELSEQDVWGKSTPAGD
EIW
Download Length: 252 bp
>AT213323 NZ_CP107532:2743248-2744342 [Methylobacterium sp. FF17]
ATGACGACGCAGGAAGCCTGGACGCCGCAATGGGCGACCCATCCCGGCGAACACCTCGAAGAGTACATCCAGGAGCGCGG
CTGGTCCCAGGCCGAGTTCGCCCGCATCGCCGACATGACGCCCAAGCTAGTCAGCACGATCATCAACGGCTCCAACCCGG
TCACGCCCGAGACCGCACTGAAGCTGGAGCACGTGCTCGGCCTCAAGGCCTACATCTGGACCGGCCTCCAGGCGAACTGG
GACCTGTTCCAGGCTCGGCAGCGGGAGCAGGAGGCGGCCGTGCGGGAGGCCGAATGGCTCAAGGGGTTCCCTATCAGGGA
ACTGAAGGCCTGTGGTCGCCTTCCCCAGACCAACGACCCCGGCAGGATCATGGACGGTCTGCTGGGCCTCCTCGGGATCG
GGGGACCGCACGCCTACGAGGCGAAGCTCGGTTCCCTGGCCGTGCACCACCGCAAGGCGAGGACCGGCACCACCTCGCCC
CACCACATGCTGTGCTGGCTGATGCTGGGCGAGGAGAAGGCGCGCCGGCTCAGCCTGCCGGCCTACGATCCGGGGCGGTT
CAAGCAGGGATGCGCAGAGATCCGTTCGCTGACCGTGGAAATGCCTGAGACCTTCGAGCCGCGCATGCTCGAAATCTGCC
ATGCGTCCGGCGTCGCCCTAGTGTTCCAGAAGCCCCTAAGCAAGACCTGCGTCTTCGGATCGGCGCGGTGGCTGAACGAC
GACCGTCCCATGATCCAGATGTCGCTGCGCATGAAGAGCAACGACCATTTCTGGTGGACCTTCTTCCACGAGGCGGCGCA
CATCAGCCTGCATCGCGGAATGAATTTCGTCGACGACAAGAACGGCGAGGACAACGACGTCGAGGCCGAGGCGGATGCCT
GGGCCGAGGAGATGCTGGTCGGGCGCGAGCGGATCGATGCCTTCGCCACCACATGCCCACGGACGAAGCAGGAGGTCGTG
ACCTTCGCCGACGAGGTCGGGCTTCATCCGGGCATCGTGGTCGGCATGCTGCAACACCGACGCGTCCTCGCATTCAGCCA
CCTGAACGACCTGAAGGCACGTTTGGGATGGGCGGACGAGGTCGCCGCCGCCTGA
ATGACGACGCAGGAAGCCTGGACGCCGCAATGGGCGACCCATCCCGGCGAACACCTCGAAGAGTACATCCAGGAGCGCGG
CTGGTCCCAGGCCGAGTTCGCCCGCATCGCCGACATGACGCCCAAGCTAGTCAGCACGATCATCAACGGCTCCAACCCGG
TCACGCCCGAGACCGCACTGAAGCTGGAGCACGTGCTCGGCCTCAAGGCCTACATCTGGACCGGCCTCCAGGCGAACTGG
GACCTGTTCCAGGCTCGGCAGCGGGAGCAGGAGGCGGCCGTGCGGGAGGCCGAATGGCTCAAGGGGTTCCCTATCAGGGA
ACTGAAGGCCTGTGGTCGCCTTCCCCAGACCAACGACCCCGGCAGGATCATGGACGGTCTGCTGGGCCTCCTCGGGATCG
GGGGACCGCACGCCTACGAGGCGAAGCTCGGTTCCCTGGCCGTGCACCACCGCAAGGCGAGGACCGGCACCACCTCGCCC
CACCACATGCTGTGCTGGCTGATGCTGGGCGAGGAGAAGGCGCGCCGGCTCAGCCTGCCGGCCTACGATCCGGGGCGGTT
CAAGCAGGGATGCGCAGAGATCCGTTCGCTGACCGTGGAAATGCCTGAGACCTTCGAGCCGCGCATGCTCGAAATCTGCC
ATGCGTCCGGCGTCGCCCTAGTGTTCCAGAAGCCCCTAAGCAAGACCTGCGTCTTCGGATCGGCGCGGTGGCTGAACGAC
GACCGTCCCATGATCCAGATGTCGCTGCGCATGAAGAGCAACGACCATTTCTGGTGGACCTTCTTCCACGAGGCGGCGCA
CATCAGCCTGCATCGCGGAATGAATTTCGTCGACGACAAGAACGGCGAGGACAACGACGTCGAGGCCGAGGCGGATGCCT
GGGCCGAGGAGATGCTGGTCGGGCGCGAGCGGATCGATGCCTTCGCCACCACATGCCCACGGACGAAGCAGGAGGTCGTG
ACCTTCGCCGACGAGGTCGGGCTTCATCCGGGCATCGTGGTCGGCATGCTGCAACACCGACGCGTCCTCGCATTCAGCCA
CCTGAACGACCTGAAGGCACGTTTGGGATGGGCGGACGAGGTCGCCGCCGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|