Detailed information of TA system TA021311

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PhoH-LOG/-
• Location: 1402078..1404393
• Replicon: chromosome
• Accession: NC_007577
• Organism: Prochlorococcus marinus str. MIT 9312

Toxin (Protein)

• Gene name: PhoH
• Uniprot ID: Q318Z1
• Locus tag: PMT9312_RS07720
• Protein ID: WP_011377037.1
• Coordinates: 1402078..1403469 (+)
• Length: 464 a.a.

Antitoxin (Protein)

• Gene name: LOG
• Uniprot ID: -
• Locus tag: PMT9312_RS07725
• Protein ID: WP_193741820.1
• Coordinates: 1403506..1404393 (+)
• Length: 296 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PMT9312_RS09920	1398167..1398322	+	156	WP_193741817.1	hypothetical protein	-
PMT9312_RS09925	1399731..1399901	+	171	WP_193741818.1	hypothetical protein	-
PMT9312_RS07710	1399950..1400057	-	108	WP_025915039.1	high light inducible protein	-
PMT9312_RS09930	1400923..1401087	+	165	WP_011377035.1	hypothetical protein	-
PMT9312_RS09935	1401288..1401434	+	147	WP_193741819.1	hypothetical protein	-
PMT9312_RS07715	1401510..1402028	+	519	WP_011377036.1	hemagglutinin	-
PMT9312_RS07720	1402078..1403469	+	1392	WP_011377037.1	PhoH family protein	Toxin
PMT9312_RS07725	1403506..1404393	+	888	WP_193741820.1	LOG family protein	Antitoxin
PMT9312_RS07730	1404720..1405034	-	315	WP_011377039.1	hypothetical protein	-
PMT9312_RS07735	1405346..1406062	+	717	WP_011377040.1	dienelactone hydrolase family protein	-
PMT9312_RS09940	1406113..1406262	+	150	WP_193741821.1	hypothetical protein	-
PMT9312_RS07740	1407113..1407454	+	342	WP_011377041.1	DUF1330 domain-containing protein	-
PMT9312_RS07745	1407588..1407890	+	303	WP_011377042.1	RNA-binding protein	-
PMT9312_RS07750	1408017..1408154	+	138	WP_011377043.1	gibberellin regulated protein-like	-
PMT9312_RS07755	1408155..1408403	+	249	WP_011377044.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-150)

Antitoxin

• LOG family (161-289)

Sequences

Toxin

Protein

• Length: 464 a.a.
• Molecular weight: 51616.07 Da
• Isoelectric Point: 9.0086

>T21311 WP_011377037.1 NC_007577:1402078-1403469 [Prochlorococcus marinus str. MIT 9312]
MKKRVIVLDTNVLLHDPESPLHFTNENVVIPIQVVEEVDRFKRDPGEKGRNARRVSRLLDGLREKGNLSSGVKINNKSEG
TIKVAFCRKETTDRLPSELSDSSGDNKILAVALEEKNTKILSDFPEVVLISKDTNLRIKADAVGLKAEDFTKDKVSLDNL
DKGFREISSNSGEINKVQKDGFIYLRDIKSKFEPSLVSNEGVILRDNLKENHTYLTRYDRSEKKLVGLNFLKRSNLGKVK
PKNLEQSFALDLLLDPKVQLVSLVGKAGTGKTLLALAVGLHQVADENLYERLLVSRPPIPLGKELGYLPGSLDEKLAPWM
KPIIDNLDYLTSPNSNKNGARVNQKERDINSKNSWEDLRGMGLLEVEAINYIRGRSIPHQFILIDEAQNLTPLEVKTIVT
RAGEGTKIVFTGDPNQIDHPYLDSDSNGLTWLAKKLHGQKIIGHITLSQGERSGLAELAADLL

Nucleotide

• Length: 1392 bp

>T21311 NC_007577:1402078-1403469 [Prochlorococcus marinus str. MIT 9312]
ATGAAAAAAAGAGTTATTGTTCTTGATACAAATGTTTTATTACATGATCCCGAGTCACCTCTACATTTTACCAATGAAAA
TGTTGTAATTCCAATTCAGGTAGTTGAAGAGGTTGATAGATTCAAAAGGGATCCTGGCGAGAAGGGACGTAATGCCAGAA
GAGTTTCAAGATTATTAGATGGTCTGCGAGAAAAAGGTAATCTATCATCGGGCGTAAAAATTAATAATAAATCTGAGGGT
ACAATAAAAGTTGCATTTTGCAGAAAAGAGACTACTGATAGATTACCATCAGAGCTTAGTGACAGTAGTGGAGATAATAA
GATTTTAGCTGTCGCTCTTGAAGAAAAAAATACCAAAATCTTATCAGACTTTCCTGAAGTCGTACTTATTTCGAAAGATA
CAAATTTAAGAATCAAAGCAGATGCTGTTGGTCTTAAAGCTGAAGATTTTACTAAAGATAAGGTTTCTTTAGATAATTTA
GATAAGGGGTTTAGGGAAATAAGTTCAAATTCAGGGGAGATAAATAAGGTTCAAAAAGATGGGTTTATTTATTTAAGAGA
TATCAAATCAAAATTTGAACCATCTTTAGTGAGTAATGAGGGTGTAATCTTGCGAGATAATTTAAAAGAGAATCATACTT
ACTTAACAAGATATGATCGATCTGAGAAAAAGTTAGTAGGTCTAAATTTTTTAAAAAGATCAAATTTAGGCAAAGTAAAA
CCTAAGAATCTTGAACAAAGTTTTGCTTTAGATTTACTCCTAGACCCAAAAGTTCAATTAGTAAGTCTTGTAGGAAAAGC
TGGGACAGGTAAAACTTTACTTGCTTTGGCAGTAGGATTACATCAAGTTGCAGACGAAAATTTATACGAAAGATTATTAG
TATCTAGACCACCAATACCTTTGGGCAAAGAATTAGGCTATCTCCCAGGTAGTCTTGATGAAAAATTAGCTCCTTGGATG
AAGCCAATAATTGATAATTTAGATTATTTAACCAGTCCAAATTCAAATAAAAATGGGGCAAGAGTTAATCAAAAAGAAAG
AGATATTAACTCTAAAAATTCATGGGAAGACTTGAGAGGCATGGGTCTCTTGGAAGTAGAAGCAATAAACTACATTAGAG
GAAGATCAATACCACATCAATTTATTCTTATTGATGAAGCCCAAAATTTAACACCTTTAGAAGTAAAAACTATCGTTACT
AGAGCTGGAGAAGGAACAAAAATTGTTTTTACAGGAGATCCAAATCAAATAGATCATCCATATCTTGATTCTGATAGTAA
CGGATTGACTTGGTTAGCTAAAAAATTACATGGTCAAAAAATAATTGGACACATAACTTTATCTCAAGGCGAGAGAAGTG
GTTTGGCAGAATTAGCGGCTGATCTTTTGTAG

Antitoxin

Protein

• Length: 296 a.a.
• Molecular weight: 33282.15 Da
• Isoelectric Point: 7.2087

>AT21311 WP_193741820.1 NC_007577:1403506-1404393 [Prochlorococcus marinus str. MIT 9312]
MENDMNDKFKCNFENERSNEVKLVASNLEAILKSSTYKLAHEDIELLNTDEMRGVRMLLEITKPEQVIEKENIISTVIVF
GGVHISEEITSKRRLDDAEQLLSSNPKSKSSKINIERLKNLHSLSHYYSAARELSKLISLDSKTKNPHSHVIVTGGGPGI
MEAANRGAFDAGCKSIGLNISLPNEQHPNSFITPGLCFKFNYFAMRKFHFVMRSAAAVFFPGGFGTLDELFELLTLRQTG
MKKNIPIILFGRSHWEKVINFQFLSDMGLIGENDLSIFQYADTAKEAWNLIKNFS

Nucleotide

• Length: 888 bp

>AT21311 NC_007577:1403506-1404393 [Prochlorococcus marinus str. MIT 9312]
ATGGAGAACGATATGAATGACAAATTTAAATGTAATTTCGAAAACGAAAGAAGTAACGAGGTTAAATTAGTTGCTAGTAA
TTTAGAAGCAATTTTAAAATCTAGTACTTATAAACTTGCTCACGAAGATATTGAATTATTGAATACTGATGAAATGCGAG
GAGTGAGGATGCTCCTTGAAATTACAAAGCCCGAACAAGTTATTGAAAAAGAAAATATAATTTCAACTGTTATTGTTTTT
GGAGGAGTCCACATATCAGAAGAAATTACCTCAAAAAGAAGGCTAGATGATGCAGAACAACTTCTTTCAAGTAATCCTAA
ATCTAAATCTTCCAAGATAAATATCGAGAGATTAAAAAATTTGCACTCCCTCTCACATTATTATTCTGCAGCAAGAGAAT
TATCTAAATTAATCTCACTGGATAGCAAAACAAAAAATCCTCATTCTCATGTAATAGTCACTGGCGGCGGACCTGGGATT
ATGGAAGCAGCTAATAGGGGAGCATTTGATGCTGGATGTAAATCGATTGGATTAAATATAAGCCTGCCCAATGAGCAACA
CCCTAATTCTTTTATTACTCCAGGATTATGTTTTAAATTTAATTATTTTGCCATGAGGAAATTTCATTTTGTTATGAGAT
CTGCTGCTGCAGTTTTTTTTCCTGGAGGATTTGGAACTCTAGATGAATTATTTGAATTATTAACATTAAGACAAACTGGG
ATGAAGAAGAATATTCCAATAATTTTATTTGGCAGAAGCCACTGGGAAAAGGTAATTAATTTTCAATTCCTATCTGATAT
GGGCTTAATTGGAGAAAATGATTTATCTATTTTTCAATACGCTGATACAGCAAAGGAAGCTTGGAATTTAATAAAAAATT
TTTCATAA

Structures

Toxin

• AlphaFold DB: Q318Z1