Detailed information of TA system TA021300

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PhoH-LOG/-
• Location: 1417660..1420005
• Replicon: chromosome
• Accession: NC_007516
• Organism: Synechococcus sp. CC9605

Toxin (Protein)

• Gene name: PhoH
• Uniprot ID: -
• Locus tag: SYNCC9605_RS07705
• Protein ID: WP_011364505.1
• Coordinates: 1418617..1420005 (-)
• Length: 463 a.a.

Antitoxin (Protein)

• Gene name: LOG
• Uniprot ID: -
• Locus tag: SYNCC9605_RS07700
• Protein ID: WP_049749460.1
• Coordinates: 1417660..1418559 (-)
• Length: 300 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SYNCC9605_RS07665	1412687..1413559	-	873	WP_011364496.1	phycobilisome rod-core linker polypeptide	-
SYNCC9605_RS13905	1413759..1413992	-	234	Protein_1570	hypothetical protein	-
SYNCC9605_RS07670	1414081..1414791	-	711	Protein_1571	response regulator transcription factor	-
SYNCC9605_RS15175	1414788..1414931	-	144	WP_198002512.1	hypothetical protein	-
SYNCC9605_RS07675	1415152..1415391	+	240	Protein_1573	hypothetical protein	-
SYNCC9605_RS07680	1415400..1415765	+	366	Protein_1574	DUF429 domain-containing protein	-
SYNCC9605_RS07685	1415845..1416072	+	228	WP_156783054.1	hypothetical protein	-
SYNCC9605_RS07690	1416991..1417170	+	180	WP_041434842.1	hypothetical protein	-
SYNCC9605_RS15180	1417213..1417389	+	177	WP_198002438.1	hypothetical protein	-
SYNCC9605_RS14710	1417492..1417659	+	168	WP_156783055.1	hypothetical protein	-
SYNCC9605_RS07700	1417660..1418559	-	900	WP_049749460.1	LOG family protein	Antitoxin
SYNCC9605_RS07705	1418617..1420005	-	1389	WP_011364505.1	PhoH family protein	Toxin
SYNCC9605_RS14715	1420005..1420166	+	162	WP_156783056.1	hypothetical protein	-
SYNCC9605_RS07710	1420890..1421243	+	354	WP_156783057.1	hypothetical protein	-
SYNCC9605_RS07720	1422507..1422767	+	261	WP_011364507.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-150)

Antitoxin

• LOG family (153-281)

Sequences

Toxin

Protein

• Length: 463 a.a.
• Molecular weight: 50550.52 Da
• Isoelectric Point: 5.9686

>T21300 WP_011364505.1 NC_007516:c1420005-1418617 [Synechococcus sp. CC9605]
MKDKIVVLDTNVLLHDPEAPHRFGDLRVVIPIQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIEGTNHG
ILQVVFCQAQALNALPAELQGGGGDNNILAVALEQMRCSGLTKAPEVVLISKDINLRIKADAVGLQAEDYVNDNVSIDDL
YAGFRQLSTDAETIKTLHDEDQLPLEAVADPEGQHLQANEGVVLVDQHNDSHTLLARHQGNSNIIKPLHWLKRAHLGRIK
ARNREQSFALDLLLDPSVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGKDIGYLPGTLEEKLGPWT
KPIIDNIDFITGSSPGGEAEQTKKQRHCEPRNAWADLQGMGLLEVEAINTIRGRSIPNQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANTL

Nucleotide

• Length: 1389 bp

>T21300 NC_007516:c1420005-1418617 [Synechococcus sp. CC9605]
ATGAAAGACAAAATTGTTGTTCTCGACACGAATGTGCTGCTCCATGATCCTGAGGCGCCGCACCGCTTTGGTGATCTCAG
GGTTGTGATCCCCATCCAAGTGGTTGAAGAAATCGATCGCTTCAAAAAGGATCACTCTGAAAAAGGCCGCAACGCTCGGC
GGATTTCAAGGCTCCTGGATTCCTACCGAGCCCGCGGAAGCCTTGCCGATGGCGTTCCGATTGAGGGCACGAATCACGGC
ATCCTGCAGGTGGTGTTCTGTCAGGCCCAAGCTCTCAACGCCTTGCCGGCAGAACTGCAGGGGGGAGGCGGCGACAACAA
CATCCTTGCGGTGGCCCTCGAGCAGATGCGATGCAGCGGGCTGACGAAGGCACCTGAGGTTGTGCTGATCAGCAAAGACA
TCAACCTGCGAATCAAGGCTGATGCGGTGGGCCTGCAGGCCGAGGACTACGTCAACGACAACGTCTCGATCGACGATCTC
TACGCAGGGTTCCGACAACTCAGCACCGATGCGGAGACGATCAAGACCCTGCATGACGAGGATCAACTCCCTTTGGAAGC
TGTCGCCGATCCCGAGGGGCAGCATCTCCAGGCCAATGAAGGTGTGGTGCTGGTGGATCAGCACAACGACAGCCACACCC
TGCTTGCCCGGCATCAAGGCAACAGCAACATCATCAAGCCGCTGCACTGGCTGAAACGCGCCCACCTGGGACGGATCAAG
GCGAGAAATCGCGAGCAAAGCTTTGCGCTGGATCTGCTGCTCGATCCCTCGGTCGCTCTGGTGACCTTGGTGGGCAAGGC
CGGCACAGGCAAAACGTTGCTGGCCATCGCCGCAGGTTTGCACCAGGTGGCCGACACCCATCACTACGCCCGCCTGTTGG
TGACGCGCCCACCGATTTCCCTCGGCAAAGACATCGGCTACCTGCCGGGCACGCTTGAGGAGAAACTCGGCCCTTGGACG
AAGCCGATCATCGACAACATCGACTTCATCACAGGTTCGTCTCCCGGCGGGGAGGCTGAGCAGACGAAGAAACAACGGCA
CTGCGAACCACGCAACGCCTGGGCTGACTTGCAAGGCATGGGCTTGCTTGAGGTTGAAGCGATCAACACCATCCGCGGCC
GATCGATTCCCAATCAGTTCCTGGTGGTGGATGAGGCGCAAAACCTCACGCCCCTGGAAGTGAAGACGATCGTGACGCGG
GTGGGGGAAGGAACCAAGGTTGTCTTCACCGGTGACCCTTATCAAATCGACAATCCCTATGTGGATGCCGAAAGCAACGG
GCTCACCTGGCTGGTGGAAAAGCTCAAAGGTCAGCCCCTGGTGGGACACATGACCCTCACCAAAGGTGAGCGCAGTGAAC
TGGCTGAACTGGCGGCCAACACCCTCTGA

Antitoxin

Protein

• Length: 300 a.a.
• Molecular weight: 32689.00 Da
• Isoelectric Point: 5.1657

>AT21300 WP_049749460.1 NC_007516:c1418559-1417660 [Synechococcus sp. CC9605]
MTQFSGTSTPEQANLGAILMSPTYRIAHEDPDLLNSNAMRGVRMLLEITKPDLHLETAGIESTIIVFGGARIIDNDTAAA
KLAQAEQRLSETPGSPVLKRQVVHAKQLVELSRFYDAAREFASLASQHGQANKGESHGCSSHVIVTGGGPGIMEAANRGA
FEVGCRSIGLNITLPFEQHPNPYITPDLCFKFNYFSLRKFHFVMRSIGAILFPGGFGTLDELFELLTLRQVGTKGSMPIV
LFGTEFWRRLVDFDYLAETGLISDDDLDLIHFSDSADEAWEFIRSRTQNDPQGGAGPAA

Nucleotide

• Length: 900 bp

>AT21300 NC_007516:c1418559-1417660 [Synechococcus sp. CC9605]
ATGACTCAATTCTCAGGCACCTCAACCCCTGAGCAAGCCAACCTGGGCGCGATTCTGATGTCCCCCACCTACCGAATTGC
CCATGAAGATCCCGACTTGCTGAACAGCAATGCCATGCGTGGTGTGCGCATGCTGCTTGAAATCACCAAGCCGGATCTGC
ATCTGGAAACAGCCGGGATCGAATCGACGATCATTGTTTTTGGTGGTGCCAGGATTATCGACAACGACACTGCAGCAGCG
AAGCTGGCGCAAGCCGAGCAACGGCTTAGTGAAACTCCAGGCTCACCGGTGTTAAAGCGACAAGTCGTCCATGCGAAACA
GCTTGTGGAGTTGTCCCGTTTTTACGATGCAGCACGGGAATTCGCCTCATTGGCGTCCCAGCACGGGCAGGCCAATAAGG
GGGAAAGCCATGGATGCTCATCCCATGTGATCGTGACCGGCGGTGGCCCGGGAATCATGGAAGCCGCCAACCGGGGTGCC
TTTGAGGTCGGCTGTCGCTCGATCGGGCTGAATATCACGCTGCCGTTTGAACAACACCCCAATCCCTACATCACCCCCGA
TCTTTGCTTCAAGTTCAACTACTTCTCACTGCGCAAATTCCATTTTGTGATGCGCTCGATTGGCGCCATCCTTTTCCCGG
GTGGCTTCGGCACGCTTGATGAACTGTTTGAGCTGCTCACCCTGCGGCAAGTGGGCACCAAAGGCAGCATGCCCATCGTG
CTGTTTGGAACAGAGTTTTGGAGGAGGCTGGTGGATTTCGACTACCTCGCCGAGACGGGCTTGATCTCAGATGACGATCT
CGATCTGATTCATTTCTCGGACTCAGCGGACGAGGCCTGGGAGTTCATCCGCAGCCGAACGCAGAACGACCCCCAGGGGG
GTGCAGGCCCAGCAGCCTGA