Detailed information of TA system TA212934

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 6695499..6696015
• Replicon: chromosome
• Accession: NZ_CP081490
• Organism: Pseudomonas protegens strain PS1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: K5F93_RS30350
• Protein ID: WP_221810054.1
• Coordinates: 6695499..6695780 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: K5F93_RS30355
• Protein ID: WP_221810055.1
• Coordinates: 6695770..6696015 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K5F93_RS30330 (K5F93_30330)	6691751..6692641	-	891	WP_221810051.1	HlyD family secretion protein	-
K5F93_RS30335 (K5F93_30335)	6692638..6692847	-	210	WP_011058538.1	DUF1656 domain-containing protein	-
K5F93_RS30340 (K5F93_30340)	6692844..6694931	-	2088	WP_221810052.1	FUSC family protein	-
K5F93_RS30345 (K5F93_30345)	6694928..6695356	-	429	WP_221810053.1	MarR family transcriptional regulator	-
K5F93_RS30350 (K5F93_30350)	6695499..6695780	-	282	WP_221810054.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K5F93_RS30355 (K5F93_30355)	6695770..6696015	-	246	WP_221810055.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
K5F93_RS30360 (K5F93_30360)	6696080..6696325	-	246	WP_221810056.1	DUF2789 domain-containing protein	-
K5F93_RS30365 (K5F93_30365)	6696340..6696630	-	291	Protein_6022	YbaK/EbsC family protein	-
K5F93_RS30370 (K5F93_30370)	6696767..6698965	+	2199	WP_221810057.1	outer membrane assembly lipoprotein YfiO	-
K5F93_RS30375 (K5F93_30375)	6698935..6699684	+	750	WP_221810058.1	DUF3142 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-81)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10756.63 Da
• Isoelectric Point: 10.2298

>T212934 WP_221810054.1 NZ_CP081490:c6695780-6695499 [Pseudomonas protegens]
MTYSLEFLPSAHKEWSKLGHTLREQFKKKLAERLEVPRIPADALHGLADCYKIKLKASGYRLVYQVIEERVVVCVVAVGK
RERGAVYEQARKR

Nucleotide

• Length: 282 bp

>T212934 NZ_CP107408:870139-870546 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCGTGC
GCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCCGAA
TGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGGACA
GCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGGCGC
AGGAGTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8697.01 Da
• Isoelectric Point: 4.5164

>AT212934 WP_221810055.1 NZ_CP081490:c6696015-6695770 [Pseudomonas protegens]
MQSILADKAVSVSELKKNPSAVLSGAQGGPVAVLNHNRVMGYMVPAEVFEALMERLDDLELAEIVRARSHEAPVPVSLDD
L

Nucleotide

• Length: 246 bp

>AT212934 NZ_CP107408:869892-870158 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA