Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 6137153..6137749 Replicon chromosome
Accession NZ_CP081490
Organism Pseudomonas protegens strain PS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K5F93_RS27840 Protein ID WP_221809720.1
Coordinates 6137153..6137455 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K5F93_RS27845 Protein ID WP_016968235.1
Coordinates 6137459..6137749 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5F93_RS27820 (K5F93_27820) 6132404..6133747 - 1344 WP_260627538.1 precorrin-3B synthase -
K5F93_RS27825 (K5F93_27825) 6133849..6135063 + 1215 WP_221809718.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
K5F93_RS27830 (K5F93_27830) 6135157..6136254 + 1098 WP_102862980.1 cobalt-precorrin-5B (C(1))-methyltransferase -
K5F93_RS27835 (K5F93_27835) 6136251..6136979 + 729 WP_221809719.1 cobalt-precorrin-6A reductase -
K5F93_RS27840 (K5F93_27840) 6137153..6137455 + 303 WP_221809720.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K5F93_RS27845 (K5F93_27845) 6137459..6137749 + 291 WP_016968235.1 putative addiction module antidote protein Antitoxin
K5F93_RS27850 (K5F93_27850) 6137849..6138247 + 399 WP_221809721.1 DUF2946 domain-containing protein -
K5F93_RS27855 (K5F93_27855) 6138312..6138791 + 480 WP_221812432.1 copper chaperone PCu(A)C -
K5F93_RS27865 (K5F93_27865) 6138903..6139400 + 498 WP_260627539.1 DUF2946 domain-containing protein -
K5F93_RS27870 (K5F93_27870) 6139489..6141621 + 2133 WP_221809722.1 TonB-dependent copper receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11663.42 Da        Isoelectric Point: 10.4917

>T212932 WP_221809720.1 NZ_CP081490:6137153-6137455 [Pseudomonas protegens]
MYVFEQTLEFSRWLLHLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVYEMRIHRGPGYRVYFSRRNTVIYLLLIGGDKG
TQRRDIQRARQLAHDLKSEG

Download         Length: 303 bp

>T212932 NZ_CP107408:326972-327340 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10409.96 Da        Isoelectric Point: 6.4594

>AT212932 WP_016968235.1 NZ_CP081490:6137459-6137749 [Pseudomonas protegens]
MHTPVTRFDAAEYLKTPEDMVAYLDACFEEDAGDGKLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLHVSPA

Download         Length: 291 bp

>AT212932 NZ_CP107408:326754-326975 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References