Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 5281177..5281690 Replicon chromosome
Accession NZ_CP081490
Organism Pseudomonas protegens strain PS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K5F93_RS23870 Protein ID WP_221809188.1
Coordinates 5281406..5281690 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K5F93_RS23865 Protein ID WP_221809187.1
Coordinates 5281177..5281416 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5F93_RS23840 (K5F93_23840) 5276373..5276891 - 519 WP_221809183.1 Hcp family type VI secretion system effector -
K5F93_RS23845 (K5F93_23845) 5277346..5278695 - 1350 WP_221809184.1 GGDEF domain-containing protein -
K5F93_RS23850 (K5F93_23850) 5278804..5279442 - 639 WP_221809185.1 LysE family translocator -
K5F93_RS23855 (K5F93_23855) 5279569..5279970 - 402 Protein_4730 VOC family protein -
K5F93_RS23860 (K5F93_23860) 5280239..5280976 - 738 WP_221809186.1 hypothetical protein -
K5F93_RS23865 (K5F93_23865) 5281177..5281416 + 240 WP_221809187.1 ribbon-helix-helix protein, CopG family Antitoxin
K5F93_RS23870 (K5F93_23870) 5281406..5281690 + 285 WP_221809188.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K5F93_RS23875 (K5F93_23875) 5281739..5282887 - 1149 WP_102878685.1 L-threonine dehydrogenase -
K5F93_RS23880 (K5F93_23880) 5283045..5284064 + 1020 WP_221812412.1 DUF4917 family protein -
K5F93_RS23885 (K5F93_23885) 5284142..5284684 - 543 WP_110651880.1 XRE family transcriptional regulator -
K5F93_RS23890 (K5F93_23890) 5284846..5285628 + 783 WP_221809189.1 aldolase -
K5F93_RS23895 (K5F93_23895) 5285661..5286548 + 888 WP_221809190.1 dihydrodipicolinate synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11012.66 Da        Isoelectric Point: 11.6993

>T212931 WP_221809188.1 NZ_CP081490:5281406-5281690 [Pseudomonas protegens]
MRIEWLRSALNNLDAEARHIAQDDPRAAGEFVRALLISIEQLAQFPSSGREGRLPGTREWVVPGWPYLIPYRVRGDRLQI
LRIFHTRRQPPARW

Download         Length: 285 bp

>T212931 NZ_CP107407:1088-1354 [Klebsiella pneumoniae]
TTGGTCTGGACGATTAACTATTCCGATCGGGCGCTCAAATCGTTACGCAAGATGGACAAACAGAACGCACGACGGATTGT
GGATTTTATGAGTTTACGCATTGCAGTTGCTGCCGATCCTCGCCAGTCAGGGAAGCCGCTCAAAGGTGAGCTGGGCGAGT
TCTGGCGCTATCGGGTGGGAGATTATCGCGTTCTGTGTGAGATCCGAGATGACGAGCTTGTTATCCTTGCCGCCACGATT
GGACATCGCCGCGAAGTTTACGACTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8619.68 Da        Isoelectric Point: 4.3085

>AT212931 WP_221809187.1 NZ_CP081490:5281177-5281416 [Pseudomonas protegens]
MSIMSLRLPDELAETLAQLAKATGRSKSFLAVDALREYLAREAWQIEEIQKALNEADAGDFASAEEVAAIAGKWTDNAH

Download         Length: 240 bp

>AT212931 NZ_CP107407:880-1104 [Klebsiella pneumoniae]
ATGCTTGCTATCCGGTTATCTGATGAGATTGAGTCCCGTCTGGACTCGCTGGCGAAGCAAACCGGCAGAACAAAGACGTT
TTATGCGCGGGAAGCAATACTGGCGCATCTGGAAGACCTGGAGGATTATTATCTTTCAGCAGAAACTGCTGCACGCGTTC
GCCGTGGTGATGAAGCAGTGCATTCGTCTGAAGACGTGAGGAAGTCACTTGGTCTGGACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References