Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 5281177..5281690 | Replicon | chromosome |
Accession | NZ_CP081490 | ||
Organism | Pseudomonas protegens strain PS1 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | K5F93_RS23870 | Protein ID | WP_221809188.1 |
Coordinates | 5281406..5281690 (+) | Length | 95 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | K5F93_RS23865 | Protein ID | WP_221809187.1 |
Coordinates | 5281177..5281416 (+) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K5F93_RS23840 (K5F93_23840) | 5276373..5276891 | - | 519 | WP_221809183.1 | Hcp family type VI secretion system effector | - |
K5F93_RS23845 (K5F93_23845) | 5277346..5278695 | - | 1350 | WP_221809184.1 | GGDEF domain-containing protein | - |
K5F93_RS23850 (K5F93_23850) | 5278804..5279442 | - | 639 | WP_221809185.1 | LysE family translocator | - |
K5F93_RS23855 (K5F93_23855) | 5279569..5279970 | - | 402 | Protein_4730 | VOC family protein | - |
K5F93_RS23860 (K5F93_23860) | 5280239..5280976 | - | 738 | WP_221809186.1 | hypothetical protein | - |
K5F93_RS23865 (K5F93_23865) | 5281177..5281416 | + | 240 | WP_221809187.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
K5F93_RS23870 (K5F93_23870) | 5281406..5281690 | + | 285 | WP_221809188.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
K5F93_RS23875 (K5F93_23875) | 5281739..5282887 | - | 1149 | WP_102878685.1 | L-threonine dehydrogenase | - |
K5F93_RS23880 (K5F93_23880) | 5283045..5284064 | + | 1020 | WP_221812412.1 | DUF4917 family protein | - |
K5F93_RS23885 (K5F93_23885) | 5284142..5284684 | - | 543 | WP_110651880.1 | XRE family transcriptional regulator | - |
K5F93_RS23890 (K5F93_23890) | 5284846..5285628 | + | 783 | WP_221809189.1 | aldolase | - |
K5F93_RS23895 (K5F93_23895) | 5285661..5286548 | + | 888 | WP_221809190.1 | dihydrodipicolinate synthase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 95 a.a. Molecular weight: 11012.66 Da Isoelectric Point: 11.6993
>T212931 WP_221809188.1 NZ_CP081490:5281406-5281690 [Pseudomonas protegens]
MRIEWLRSALNNLDAEARHIAQDDPRAAGEFVRALLISIEQLAQFPSSGREGRLPGTREWVVPGWPYLIPYRVRGDRLQI
LRIFHTRRQPPARW
MRIEWLRSALNNLDAEARHIAQDDPRAAGEFVRALLISIEQLAQFPSSGREGRLPGTREWVVPGWPYLIPYRVRGDRLQI
LRIFHTRRQPPARW
Download Length: 285 bp
>T212931 NZ_CP107407:1088-1354 [Klebsiella pneumoniae]
TTGGTCTGGACGATTAACTATTCCGATCGGGCGCTCAAATCGTTACGCAAGATGGACAAACAGAACGCACGACGGATTGT
GGATTTTATGAGTTTACGCATTGCAGTTGCTGCCGATCCTCGCCAGTCAGGGAAGCCGCTCAAAGGTGAGCTGGGCGAGT
TCTGGCGCTATCGGGTGGGAGATTATCGCGTTCTGTGTGAGATCCGAGATGACGAGCTTGTTATCCTTGCCGCCACGATT
GGACATCGCCGCGAAGTTTACGACTGA
TTGGTCTGGACGATTAACTATTCCGATCGGGCGCTCAAATCGTTACGCAAGATGGACAAACAGAACGCACGACGGATTGT
GGATTTTATGAGTTTACGCATTGCAGTTGCTGCCGATCCTCGCCAGTCAGGGAAGCCGCTCAAAGGTGAGCTGGGCGAGT
TCTGGCGCTATCGGGTGGGAGATTATCGCGTTCTGTGTGAGATCCGAGATGACGAGCTTGTTATCCTTGCCGCCACGATT
GGACATCGCCGCGAAGTTTACGACTGA
Antitoxin
Download Length: 80 a.a. Molecular weight: 8619.68 Da Isoelectric Point: 4.3085
>AT212931 WP_221809187.1 NZ_CP081490:5281177-5281416 [Pseudomonas protegens]
MSIMSLRLPDELAETLAQLAKATGRSKSFLAVDALREYLAREAWQIEEIQKALNEADAGDFASAEEVAAIAGKWTDNAH
MSIMSLRLPDELAETLAQLAKATGRSKSFLAVDALREYLAREAWQIEEIQKALNEADAGDFASAEEVAAIAGKWTDNAH
Download Length: 240 bp
>AT212931 NZ_CP107407:880-1104 [Klebsiella pneumoniae]
ATGCTTGCTATCCGGTTATCTGATGAGATTGAGTCCCGTCTGGACTCGCTGGCGAAGCAAACCGGCAGAACAAAGACGTT
TTATGCGCGGGAAGCAATACTGGCGCATCTGGAAGACCTGGAGGATTATTATCTTTCAGCAGAAACTGCTGCACGCGTTC
GCCGTGGTGATGAAGCAGTGCATTCGTCTGAAGACGTGAGGAAGTCACTTGGTCTGGACGATTAA
ATGCTTGCTATCCGGTTATCTGATGAGATTGAGTCCCGTCTGGACTCGCTGGCGAAGCAAACCGGCAGAACAAAGACGTT
TTATGCGCGGGAAGCAATACTGGCGCATCTGGAAGACCTGGAGGATTATTATCTTTCAGCAGAAACTGCTGCACGCGTTC
GCCGTGGTGATGAAGCAGTGCATTCGTCTGAAGACGTGAGGAAGTCACTTGGTCTGGACGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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