Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PfiT-PfiA/- |
Location | 124700..125305 | Replicon | chromosome |
Accession | NZ_CP081490 | ||
Organism | Pseudomonas protegens strain PS1 |
Toxin (Protein)
Gene name | PfiT | Uniprot ID | - |
Locus tag | K5F93_RS00595 | Protein ID | WP_060844990.1 |
Coordinates | 124961..125305 (+) | Length | 115 a.a. |
Antitoxin (Protein)
Gene name | PfiA | Uniprot ID | A0A7Y1CEW2 |
Locus tag | K5F93_RS00590 | Protein ID | WP_025131512.1 |
Coordinates | 124700..124948 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K5F93_RS00565 (K5F93_00565) | 120013..121020 | - | 1008 | WP_221810226.1 | NAD(P)-dependent oxidoreductase | - |
K5F93_RS00570 (K5F93_00570) | 121020..122033 | - | 1014 | WP_221810227.1 | beta-ketoacyl-ACP synthase 3 | - |
K5F93_RS00575 (K5F93_00575) | 122081..122728 | - | 648 | WP_221810228.1 | YcxB family protein | - |
K5F93_RS00580 (K5F93_00580) | 122826..123605 | - | 780 | WP_260627384.1 | hypothetical protein | - |
K5F93_RS00585 (K5F93_00585) | 123737..124090 | - | 354 | WP_221810229.1 | DUF3077 domain-containing protein | - |
K5F93_RS00590 (K5F93_00590) | 124700..124948 | + | 249 | WP_025131512.1 | prevent-host-death protein | Antitoxin |
K5F93_RS00595 (K5F93_00595) | 124961..125305 | + | 345 | WP_060844990.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
K5F93_RS00600 (K5F93_00600) | 125457..126881 | - | 1425 | WP_159894151.1 | aspartate ammonia-lyase | - |
K5F93_RS00605 (K5F93_00605) | 127063..127980 | + | 918 | WP_102862325.1 | LysR substrate-binding domain-containing protein | - |
K5F93_RS00610 (K5F93_00610) | 128439..128930 | + | 492 | WP_016967060.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
K5F93_RS00615 (K5F93_00615) | 128942..130024 | + | 1083 | WP_221810230.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 115 a.a. Molecular weight: 12868.57 Da Isoelectric Point: 4.2876
>T212927 WP_060844990.1 NZ_CP081490:124961-125305 [Pseudomonas protegens]
MPTLTIRYTETAQQSIEDQIVHLADYSDLKSAFERLDAVIDALQDKLLSAPLGYPVSPQASDLGILHYRELNTDGYRVFY
EIVDADQAIVVGLVLRDKQSVEQALIRYCLLHTD
MPTLTIRYTETAQQSIEDQIVHLADYSDLKSAFERLDAVIDALQDKLLSAPLGYPVSPQASDLGILHYRELNTDGYRVFY
EIVDADQAIVVGLVLRDKQSVEQALIRYCLLHTD
Download Length: 345 bp
>T212927 NZ_CP107403:4756735-4756837 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 83 a.a. Molecular weight: 9410.89 Da Isoelectric Point: 9.8184
>AT212927 WP_025131512.1 NZ_CP081490:124700-124948 [Pseudomonas protegens]
MRVETVSFLKRYASDLPLEEPMVVTQNGVPVYVVESYVERKRRDEAVALVKLLAVSSREYAQGKHCSTDELKARLSKRFA
HK
MRVETVSFLKRYASDLPLEEPMVVTQNGVPVYVVESYVERKRRDEAVALVKLLAVSSREYAQGKHCSTDELKARLSKRFA
HK
Download Length: 249 bp
>AT212927 NZ_CP107403:c4756844-4756699 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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