Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 108447..110155 Replicon chromosome
Accession NZ_CP081490
Organism Pseudomonas protegens strain PS1

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag K5F93_RS00510 Protein ID WP_221810217.1
Coordinates 109277..110155 (-) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag K5F93_RS00505 Protein ID WP_221810216.1
Coordinates 108447..109280 (-) Length 278 a.a.

Genomic Context

K5F93_RS00485K5F93_RS00490K5F93_RS00495K5F93_RS00500K5F93_RS00505K5F93_RS00510K5F93_RS00515K5F93_RS00520K5F93_RS00525K5F93_RS00530K5F93_RS00535
Location: 103580..105076 (1497 bp)
Type: Others
Protein ID: WP_221810213.1
Location: 105159..105962 (804 bp)
Type: Others
Protein ID: WP_102862343.1
Location: 105973..107655 (1683 bp)
Type: Others
Protein ID: WP_221810214.1
Location: 107648..108445 (798 bp)
Type: Others
Protein ID: WP_221810215.1
Location: 108447..109280 (834 bp)
Type: Antitoxin
Protein ID: WP_221810216.1
Location: 109277..110155 (879 bp)
Type: Toxin
Protein ID: WP_221810217.1
Location: 110160..110696 (537 bp)
Type: Others
Protein ID: WP_221810218.1
Location: 110709..111473 (765 bp)
Type: Others
Protein ID: WP_221812263.1
Location: 111473..112249 (777 bp)
Type: Others
Protein ID: WP_221812264.1
Location: 112279..113280 (1002 bp)
Type: Others
Protein ID: WP_221810219.1
Location: 113320..114156 (837 bp)
Type: Others
Protein ID: WP_260627543.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
K5F93_RS00485 (K5F93_00485)103580..105076-1497WP_221810213.1aldehyde dehydrogenase-
K5F93_RS00490 (K5F93_00490)105159..105962-804WP_102862343.1aspartate dehydrogenase-
K5F93_RS00495 (K5F93_00495)105973..107655-1683WP_221810214.1thiamine pyrophosphate-binding protein-
K5F93_RS00500 (K5F93_00500)107648..108445-798WP_221810215.1SDR family oxidoreductase-
K5F93_RS00505 (K5F93_00505)108447..109280-834WP_221810216.1IclR family transcriptional regulatorAntitoxin
K5F93_RS00510 (K5F93_00510)109277..110155-879WP_221810217.1alpha/beta fold hydrolaseToxin
K5F93_RS00515 (K5F93_00515)110160..110696-537WP_221810218.1cupin domain-containing protein-
K5F93_RS00520 (K5F93_00520)110709..111473-765WP_221812263.1SDR family oxidoreductase-
K5F93_RS00525 (K5F93_00525)111473..112249-777WP_221812264.1ABC transporter permease-
K5F93_RS00530 (K5F93_00530)112279..113280-1002WP_221810219.1ABC transporter substrate-binding protein-
K5F93_RS00535 (K5F93_00535)113320..114156-837WP_260627543.1ABC transporter ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-276)

Antitoxin

Transcription regulator IclR, C-terminal

(134-256)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 31130.76 Da        Isoelectric Point: 8.0022

>T212926 WP_221810217.1 NZ_CP081490:c110155-109277 [Pseudomonas protegens]
MLPGRSQAASTADLQAQLARDFPLQRVLAAGGQQTLRECGTGPAVVLLHGIGSAAASWLQVAQQLAPKARVIAWDAPGYG
ESSPLESPAPKAEQYATRLMQMLDALDVEQCVLVGHSLGALPALAFARSSQAPRVSRLLLISPTRGYGASERALQRQQVR
QQRLDNLEHLGIAGLADQRTAHMLSANAAPRALAWVHWNMARLNPAGYRQAIELLCGDDLLRHGPPDMPCEVHCGEFDRI
TPAQTCLTLAKALGASFNLIADAGHASPVEQPLVVAGRLAFAIKESMTGRPL

Download         Length: 879 bp

>T212926 NZ_CP107403:3611056-3611463 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCGTGC
GCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCCGAA
TGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGGACA
GCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGGCGC
AGGAGTAA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30390.86 Da        Isoelectric Point: 6.9725

>AT212926 WP_221810216.1 NZ_CP081490:c109280-108447 [Pseudomonas protegens]
MNDADLLKDPQDKYIVPGLERGLLLLCEFSRSNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVSVGTRLPAHATVLGRVLLGDLSLA
ELRELYPEEHLEQHSPSTPNTVMALFDMVQADRQRGFVSGEGFFEPSISTVAAPVRDQSGGIVAALGVTIATAQVGHINY
NELLLQVRRSADELSRLLNYNSAAHGGQPRVTALMRD

Download         Length: 834 bp

>AT212926 NZ_CP107403:3610809-3611075 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References