212883

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6079022..6079541 Replicon chromosome
Accession NZ_CP081457
Organism Pseudomonas syringae pv. actinidifoliorum ICMP 18803

Toxin (Protein)


Gene name relE Uniprot ID S6W9N2
Locus tag A237_RS26750 Protein ID WP_017684310.1
Coordinates 6079022..6079312 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag A237_RS26755 Protein ID WP_002551444.1
Coordinates 6079302..6079541 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A237_RS26720 (A237_026615) 6075362..6075871 + 510 WP_229614215.1 hypothetical protein -
A237_RS26725 (A237_026620) 6075966..6076595 + 630 WP_005737223.1 NAD(P)H-dependent oxidoreductase -
A237_RS26730 (A237_026625) 6076654..6077268 - 615 WP_017702071.1 histidine phosphatase family protein -
A237_RS26735 (A237_026630) 6077361..6077702 - 342 WP_003380754.1 DUF5713 family protein -
A237_RS26740 (A237_026635) 6078059..6078796 + 738 WP_005737225.1 hypothetical protein -
A237_RS26745 6078818..6078937 - 120 Protein_5271 GNAT family N-acetyltransferase -
A237_RS26750 (A237_026640) 6079022..6079312 - 291 WP_017684310.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A237_RS26755 (A237_026645) 6079302..6079541 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
A237_RS26760 (A237_026650) 6079717..6080193 - 477 WP_017702070.1 GNAT family N-acetyltransferase -
A237_RS26765 (A237_026655) 6080298..6081749 - 1452 WP_017702069.1 putative DNA binding domain-containing protein -
A237_RS26770 (A237_026660) 6081742..6082374 - 633 WP_005621703.1 DUF4062 domain-containing protein -
A237_RS26775 (A237_026665) 6082562..6083101 - 540 WP_017702068.1 GNAT family N-acetyltransferase -
A237_RS26780 (A237_026670) 6083262..6083756 + 495 WP_005621707.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11145.98 Da        Isoelectric Point: 10.0984

>T212883 WP_017684310.1 NZ_CP081457:c6079312-6079022 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLGG

Download         Length: 291 bp

>T212883 NZ_CP107391:c79165-79016 [Klebsiella pneumoniae]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGTGCCACGGTATTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT212883 WP_002551444.1 NZ_CP081457:c6079541-6079302 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT212883 NZ_CP107391:79210-79269 [Klebsiella pneumoniae]
TAAGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8M1I3

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References