Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 4495082..4495670 | Replicon | chromosome |
Accession | NZ_CP081457 | ||
Organism | Pseudomonas syringae pv. actinidifoliorum ICMP 18803 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | A237_RS19720 | Protein ID | WP_020319421.1 |
Coordinates | 4495368..4495670 (-) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | A237_RS19715 | Protein ID | WP_003373299.1 |
Coordinates | 4495082..4495375 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A237_RS19685 (A237_019635) | 4490226..4491080 | + | 855 | WP_020319428.1 | LysR substrate-binding domain-containing protein | - |
A237_RS19690 (A237_019640) | 4491070..4491816 | - | 747 | WP_011103701.1 | sulfite exporter TauE/SafE family protein | - |
A237_RS19695 (A237_019645) | 4492001..4492474 | + | 474 | WP_017700784.1 | MarR family transcriptional regulator | - |
A237_RS19700 (A237_019650) | 4492688..4493107 | + | 420 | WP_003373293.1 | organic hydroperoxide resistance protein | - |
A237_RS19705 (A237_019655) | 4493148..4494167 | + | 1020 | WP_017700785.1 | alpha/beta hydrolase | - |
A237_RS19710 (A237_019660) | 4494258..4494827 | - | 570 | WP_005616505.1 | elongation factor P | - |
A237_RS19715 (A237_019665) | 4495082..4495375 | - | 294 | WP_003373299.1 | putative addiction module antidote protein | Antitoxin |
A237_RS19720 (A237_019670) | 4495368..4495670 | - | 303 | WP_020319421.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
A237_RS19725 (A237_019675) | 4495826..4496965 | - | 1140 | WP_017700787.1 | elongation factor P maturation arginine rhamnosyltransferase EarP | - |
A237_RS19730 (A237_019680) | 4497161..4497565 | + | 405 | WP_017700788.1 | hypothetical protein | - |
A237_RS19735 (A237_019685) | 4497569..4498051 | + | 483 | WP_003373305.1 | elongation factor GreAB | - |
A237_RS19740 (A237_019690) | 4498175..4498381 | + | 207 | WP_002554553.1 | hypothetical protein | - |
A237_RS19745 (A237_019695) | 4498457..4499734 | - | 1278 | WP_017700789.1 | aromatic amino acid transport family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11242.92 Da Isoelectric Point: 10.0055
>T212881 WP_020319421.1 NZ_CP081457:c4495670-4495368 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MIEIKQTAIFMAWERKLQDDRARAAIAARLFRLANGLAGDVRPVGRGVSELRVHYGPGYRIYFQQRGSELVILLCGGNKG
SQSRDIEKAKELACNWSPHD
MIEIKQTAIFMAWERKLQDDRARAAIAARLFRLANGLAGDVRPVGRGVSELRVHYGPGYRIYFQQRGSELVILLCGGNKG
SQSRDIEKAKELACNWSPHD
Download Length: 303 bp
>T212881 NZ_CP107390:3435321-3435854 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10433.84 Da Isoelectric Point: 4.2558
>AT212881 WP_003373299.1 NZ_CP081457:c4495375-4495082 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MTEQLYAYDPAEALTSPEAIAEFMTDAFASGDVGYIAKALGVVARARGMTDMARETGLSREQLYRSFSEEGNPTLKTLLA
VMQVIGLDITAQPRAAT
MTEQLYAYDPAEALTSPEAIAEFMTDAFASGDVGYIAKALGVVARARGMTDMARETGLSREQLYRSFSEEGNPTLKTLLA
VMQVIGLDITAQPRAAT
Download Length: 294 bp
>AT212881 NZ_CP107390:3435044-3435310 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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