Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4495082..4495670 Replicon chromosome
Accession NZ_CP081457
Organism Pseudomonas syringae pv. actinidifoliorum ICMP 18803

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag A237_RS19720 Protein ID WP_020319421.1
Coordinates 4495368..4495670 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag A237_RS19715 Protein ID WP_003373299.1
Coordinates 4495082..4495375 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A237_RS19685 (A237_019635) 4490226..4491080 + 855 WP_020319428.1 LysR substrate-binding domain-containing protein -
A237_RS19690 (A237_019640) 4491070..4491816 - 747 WP_011103701.1 sulfite exporter TauE/SafE family protein -
A237_RS19695 (A237_019645) 4492001..4492474 + 474 WP_017700784.1 MarR family transcriptional regulator -
A237_RS19700 (A237_019650) 4492688..4493107 + 420 WP_003373293.1 organic hydroperoxide resistance protein -
A237_RS19705 (A237_019655) 4493148..4494167 + 1020 WP_017700785.1 alpha/beta hydrolase -
A237_RS19710 (A237_019660) 4494258..4494827 - 570 WP_005616505.1 elongation factor P -
A237_RS19715 (A237_019665) 4495082..4495375 - 294 WP_003373299.1 putative addiction module antidote protein Antitoxin
A237_RS19720 (A237_019670) 4495368..4495670 - 303 WP_020319421.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A237_RS19725 (A237_019675) 4495826..4496965 - 1140 WP_017700787.1 elongation factor P maturation arginine rhamnosyltransferase EarP -
A237_RS19730 (A237_019680) 4497161..4497565 + 405 WP_017700788.1 hypothetical protein -
A237_RS19735 (A237_019685) 4497569..4498051 + 483 WP_003373305.1 elongation factor GreAB -
A237_RS19740 (A237_019690) 4498175..4498381 + 207 WP_002554553.1 hypothetical protein -
A237_RS19745 (A237_019695) 4498457..4499734 - 1278 WP_017700789.1 aromatic amino acid transport family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-91)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11242.92 Da        Isoelectric Point: 10.0055

>T212881 WP_020319421.1 NZ_CP081457:c4495670-4495368 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MIEIKQTAIFMAWERKLQDDRARAAIAARLFRLANGLAGDVRPVGRGVSELRVHYGPGYRIYFQQRGSELVILLCGGNKG
SQSRDIEKAKELACNWSPHD

Download         Length: 303 bp

>T212881 NZ_CP107390:3435321-3435854 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10433.84 Da        Isoelectric Point: 4.2558

>AT212881 WP_003373299.1 NZ_CP081457:c4495375-4495082 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MTEQLYAYDPAEALTSPEAIAEFMTDAFASGDVGYIAKALGVVARARGMTDMARETGLSREQLYRSFSEEGNPTLKTLLA
VMQVIGLDITAQPRAAT

Download         Length: 294 bp

>AT212881 NZ_CP107390:3435044-3435310 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References