212880

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 4399457..4400068 Replicon chromosome
Accession NZ_CP081457
Organism Pseudomonas syringae pv. actinidifoliorum ICMP 18803

Toxin (Protein)


Gene name PfiT Uniprot ID A0A3M4KYI7
Locus tag A237_RS19205 Protein ID WP_017701099.1
Coordinates 4399718..4400068 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A3M4KYK1
Locus tag A237_RS19200 Protein ID WP_005735310.1
Coordinates 4399457..4399705 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A237_RS19185 (A237_019140) 4395522..4395911 - 390 WP_017701102.1 DUF2946 domain-containing protein -
A237_RS19190 (A237_019145) 4396152..4396412 + 261 WP_017703409.1 DUF6429 family protein -
A237_RS19195 (A237_019150) 4396740..4399154 + 2415 WP_017701100.1 DUF3772 domain-containing protein -
A237_RS19200 (A237_019155) 4399457..4399705 + 249 WP_005735310.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
A237_RS19205 (A237_019160) 4399718..4400068 + 351 WP_017701099.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A237_RS19210 (A237_019165) 4400174..4400470 - 297 WP_020324172.1 hypothetical protein -
A237_RS19220 (A237_019175) 4403354..4403743 - 390 WP_017703339.1 hypothetical protein -
A237_RS19225 4403940..4404221 + 282 Protein_3785 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12832.63 Da        Isoelectric Point: 4.1824

>T212880 WP_017701099.1 NZ_CP081457:4399718-4400068 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MNTFALSFTDVAQQSLEDQVEHLAVTQGFSSAAQRIDTLIDAIQDKLISTPLGYPVSPQLSELGVLHYRELNTDGYRIFY
EVMDSDGITDIAVLLVLGGKKSVEQALIRYCLLQPI

Download         Length: 351 bp

>T212880 NZ_CP081457:4399718-4400068 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
ATGAATACGTTTGCACTGAGCTTTACTGATGTTGCTCAGCAAAGCCTCGAAGATCAGGTTGAACACCTGGCTGTCACTCA
GGGATTCTCATCAGCGGCTCAACGCATAGATACCCTGATTGATGCCATCCAGGATAAGCTCATATCCACCCCGTTGGGCT
ACCCGGTCAGTCCTCAATTGAGTGAGCTGGGCGTACTGCACTATCGTGAGTTGAACACAGACGGATACCGGATCTTTTAC
GAGGTCATGGATTCTGATGGTATTACCGACATCGCCGTATTGCTCGTATTAGGCGGGAAAAAAAGTGTTGAACAAGCCCT
GATCCGCTATTGCCTTCTTCAGCCTATATAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9359.74 Da        Isoelectric Point: 9.8452

>AT212880 WP_005735310.1 NZ_CP081457:4399457-4399705 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MRVETISYLKRNAADLPLDEPLIVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYAQGKHCSTDELKARLSRRFA
HK

Download         Length: 249 bp

>AT212880 NZ_CP081457:4399457-4399705 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
ATGCGAGTTGAAACAATAAGTTATCTGAAACGCAACGCAGCCGACCTGCCTCTCGATGAGCCACTGATTGTCACGCAAAA
CGGTGTCCCGGCCTATGTGGTGGAGTCTTACGCAGATCGTAAGCGCCGCGATGAGTCGATCGCCTTGGTGAAGCTCTTGG
CGATCAGTTCCCGCGAGTACGCCCAAGGCAAGCACTGTTCCACTGACGAACTCAAAGCCCGATTGAGCAGGAGGTTTGCC
CACAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M4KYI7

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4KYK1

References