Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 1082125..1082666 | Replicon | chromosome |
Accession | NZ_CP081457 | ||
Organism | Pseudomonas syringae pv. actinidifoliorum ICMP 18803 |
Toxin (Protein)
Gene name | relE | Uniprot ID | S6UY68 |
Locus tag | A237_RS04975 | Protein ID | WP_017700185.1 |
Coordinates | 1082125..1082400 (-) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A0K8LU58 |
Locus tag | A237_RS04980 | Protein ID | WP_003382249.1 |
Coordinates | 1082400..1082666 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A237_RS04955 (A237_004945) | 1077256..1078281 | - | 1026 | WP_017700182.1 | TRAP transporter substrate-binding protein | - |
A237_RS04960 (A237_004950) | 1078338..1079222 | - | 885 | WP_017700183.1 | SMP-30/gluconolactonase/LRE family protein | - |
A237_RS04965 (A237_004955) | 1079279..1080106 | - | 828 | WP_017700184.1 | NAD(P)-dependent oxidoreductase | - |
A237_RS04970 (A237_004960) | 1080285..1081553 | - | 1269 | WP_017698468.1 | OprD family porin | - |
A237_RS04975 (A237_004965) | 1082125..1082400 | - | 276 | WP_017700185.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
A237_RS04980 (A237_004970) | 1082400..1082666 | - | 267 | WP_003382249.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
A237_RS04985 (A237_004975) | 1082829..1084751 | - | 1923 | WP_017700186.1 | methyl-accepting chemotaxis protein | - |
A237_RS04990 (A237_004980) | 1085110..1086990 | + | 1881 | WP_003382247.1 | methyl-accepting chemotaxis protein | - |
A237_RS04995 (A237_004985) | 1087118..1087381 | - | 264 | WP_017700187.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10738.41 Da Isoelectric Point: 7.0123
>T212876 WP_017700185.1 NZ_CP081457:c1082400-1082125 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MELMWTSKALSDVARLYDFLAVANQPAAAQTVQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR
MELMWTSKALSDVARLYDFLAVANQPAAAQTVQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR
Download Length: 276 bp
>T212876 NZ_CP107390:c2373114-2372767 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATGCCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTGTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGTGGGCAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA
ATGTGGGATGTAGAAACGACGGATACGTTTGATGCCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTGTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGTGGGCAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 9934.24 Da Isoelectric Point: 5.7066
>AT212876 WP_003382249.1 NZ_CP081457:c1082666-1082400 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR
Download Length: 267 bp
>AT212876 NZ_CP107390:c2372767-2372468 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3M4KLP6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8LU58 |