Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2278739..2278907 Replicon chromosome
Accession NZ_CP081351
Organism Klebsiella michiganensis strain CCRI-24235

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2278797..2278900 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2278739..2278907 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Km24235_RS10910 (Km24235_2152) 2273866..2275926 + 2061 WP_014229840.1 oligopeptidase B -
Km24235_RS10915 (Km24235_2153) 2275933..2276592 - 660 WP_014229839.1 exodeoxyribonuclease X -
Km24235_RS10920 (Km24235_2154) 2276671..2276901 - 231 WP_004103351.1 DNA polymerase III subunit theta -
Km24235_RS10925 (Km24235_2155) 2277037..2277411 + 375 WP_014229838.1 CopC domain-containing protein YobA -
Km24235_RS10930 (Km24235_2156) 2277416..2278285 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
Km24235_RS10935 (Km24235_2157) 2278302..2278640 + 339 WP_004103344.1 YebY family protein -
- 2278739..2278907 - 169 - - Antitoxin
- 2278797..2278900 + 104 - - Toxin
Km24235_RS10940 (Km24235_2158) 2279025..2279984 - 960 WP_042945476.1 spore coat protein U domain-containing protein -
Km24235_RS10945 (Km24235_2159) 2279999..2282329 - 2331 WP_195377939.1 fimbria/pilus outer membrane usher protein -
Km24235_RS10950 (Km24235_2160) 2282332..2283096 - 765 WP_222582357.1 molecular chaperone -
Km24235_RS10955 (Km24235_2161) 2283115..2283633 - 519 WP_064358186.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T212850 NZ_CP081351:2278797-2278900 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT212850 NZ_CP081351:c2278907-2278739 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References