Detailed information of TA system TA021285

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 5104053..5105632
• Replicon: chromosome
• Accession: NC_007508
• Organism: Xanthomonas campestris pv. vesicatoria str. 85-10 (Xanthomonas)

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: IS_RS23250
• Protein ID: WP_129111554.1
• Coordinates: 5104053..5105318 (+)
• Length: 422 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: Q3BM53
• Locus tag: IS_RS23255
• Protein ID: WP_011349168.1
• Coordinates: 5105336..5105632 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IS_RS23240	5099849..5101399	+	1551	WP_170808575.1	hypothetical protein	-
IS_RS25685	5101752..5102602	+	851	Protein_4280	hypothetical protein	-
IS_RS23245	5103069..5103905	+	837	Protein_4281	restriction endonuclease	-
IS_RS23250	5104053..5105318	+	1266	WP_129111554.1	zeta toxin family protein	Toxin
IS_RS23255	5105336..5105632	+	297	WP_011349168.1	hypothetical protein	Antitoxin
IS_RS23260	5106155..5106564	+	410	Protein_4284	hypothetical protein	-
IS_RS23265	5106734..5107210	-	477	WP_011349170.1	nuclear transport factor 2 family protein	-
IS_RS23270	5107274..5107843	-	570	WP_011349171.1	TetR/AcrR family transcriptional regulator	-
IS_RS23275	5107960..5108532	-	573	WP_041855097.1	TetR/AcrR family transcriptional regulator	-
IS_RS23280	5108616..5109356	+	741	WP_011349173.1	glucose 1-dehydrogenase	-
IS_RS23285	5109722..5110240	-	519	WP_041855098.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	5093365..5110546	17181

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (151-291)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 422 a.a.
• Molecular weight: 45183.56 Da
• Isoelectric Point: 6.1927

>T21285 WP_129111554.1 NC_007508:5104053-5105318 [Xanthomonas campestris pv. vesicatoria str. 85-10]
IKNKIGIAGTAGLFTSHVPFDDAESKGVQAESSQAAPEYKFQTQLDNLPARPASSKSSNTTHAYVHASPPHSVPIAGAST
AAVTHQQATQLKGTDELYGLGNLPSSGPGRWEYLANPENWHPERRKLHEKLLDEARSSALTLAESLERDGCQPTLFALRG
NTATGKTRIATKKIPALAAALEKTGGKGCINPDVFKSSLAKSEAGAKIFSSAQVHNESCFLADHFEDGLRSQRTGSGAIA
SIVVDKRLARAYEIDSYIELAKETGRKVELCDIDAPLENSLTGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMSVIDRFI
ADPSLGNYRLFGTAEDGKKVMVASVMGGELSVEDADLYEKITSPQSSVTGDLADKIIDNELIDRLTNNIDDPERAANTRA
ALEKYNGKSWSAALAAHSELI

Nucleotide

• Length: 1266 bp

>T21285 NC_007508:5104053-5105318 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATAAAAAACAAGATAGGCATTGCTGGCACAGCCGGGCTTTTTACTTCTCATGTTCCTTTCGATGACGCAGAATCCAAAGG
CGTCCAAGCTGAGTCATCACAAGCGGCGCCGGAGTATAAATTCCAGACCCAGCTTGATAATTTGCCAGCTAGACCCGCTA
GTTCGAAGAGCAGCAACACCACTCATGCTTATGTTCATGCATCGCCGCCGCATTCGGTGCCGATCGCAGGTGCATCGACC
GCCGCGGTGACACATCAACAGGCTACTCAGCTTAAAGGCACCGATGAGTTATATGGTTTGGGCAACCTCCCATCTTCTGG
TCCGGGGCGATGGGAGTATCTGGCGAATCCGGAGAACTGGCATCCGGAGCGCCGTAAGTTGCACGAAAAGCTATTAGATG
AAGCACGATCTTCGGCCTTGACCCTGGCAGAATCTCTTGAGCGCGATGGCTGCCAACCGACATTGTTTGCGTTGCGCGGA
AACACTGCCACGGGTAAGACGCGGATAGCCACAAAAAAAATTCCAGCTCTCGCCGCAGCTCTGGAGAAGACAGGTGGGAA
AGGTTGCATCAATCCAGATGTATTCAAGAGTTCGCTTGCGAAGTCGGAGGCCGGCGCCAAGATATTTAGCTCGGCGCAAG
TTCATAACGAATCATGTTTTCTTGCTGACCATTTTGAAGACGGGCTTCGCTCTCAAAGGACGGGCAGCGGTGCAATCGCT
AGCATTGTTGTCGACAAGCGCTTGGCAAGGGCGTACGAAATCGACAGCTATATAGAACTAGCCAAAGAAACAGGTCGAAA
AGTTGAATTGTGCGATATCGATGCACCCCTTGAGAATTCTTTGACGGGAGTTTTGCAACGGAAACCTGAAGGTGAAGATC
CTAGGCCTCCTTACCCTGTAGTCTCGAGTGGATTTGTGGCCGTACGAAGCAATAGAATGAGTGTGATAGACAGGTTCATC
GCCGATCCGAGCCTGGGAAACTATCGACTATTCGGAACAGCCGAGGATGGTAAGAAGGTCATGGTTGCTAGCGTCATGGG
CGGTGAGTTGAGTGTAGAGGATGCTGATTTATATGAAAAGATAACGTCCCCGCAGTCCTCGGTTACCGGTGATTTGGCTG
ATAAGATAATCGACAATGAATTGATTGATCGTCTGACAAATAATATAGATGATCCCGAGCGCGCGGCGAATACGCGAGCC
GCGCTGGAAAAATATAACGGCAAGTCGTGGTCGGCCGCGCTAGCTGCTCATAGCGAGCTAATTTGA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11347.05 Da
• Isoelectric Point: 8.0069

>AT21285 WP_011349168.1 NC_007508:5105336-5105632 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MKTLKGAEALEFHKKLKGRNEALHASDIASALVRADAVGKERFDLEELEKLCYTSSAGRLTDVKERRDIYERMYYVEYPK
IMTLKEFARIVETLSSWS

Nucleotide

• Length: 297 bp

>AT21285 NC_007508:5105336-5105632 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGAAAACTTTGAAAGGCGCAGAGGCGCTCGAATTCCATAAGAAGCTTAAGGGACGCAATGAAGCCTTACATGCTTCCGA
TATCGCGTCAGCATTAGTACGCGCCGATGCCGTCGGCAAGGAACGGTTTGATCTCGAGGAACTGGAAAAACTTTGCTATA
CCAGTAGTGCGGGGCGCCTTACTGATGTGAAAGAGCGCCGCGACATATATGAGCGGATGTACTACGTCGAGTATCCTAAA
ATTATGACGTTAAAGGAATTTGCTCGTATCGTTGAGACACTTTCCTCTTGGTCATGA

Structures

Antitoxin

• AlphaFold DB: Q3BM53