21284

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4697675..4698036 Replicon chromosome
Accession NC_007508
Organism Xanthomonas campestris pv. vesicatoria str. 85-10 (Xanthomonas)

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag IS_RS21640 Protein ID WP_005914328.1
Coordinates 4697675..4697809 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q3BN31
Locus tag IS_RS21645 Protein ID WP_011348912.1
Coordinates 4697884..4698036 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS_RS21625 4694709..4695731 - 1023 WP_011348910.1 MBL fold metallo-hydrolase -
IS_RS21630 4695782..4697071 - 1290 WP_011348911.1 tryptophan--tRNA ligase -
IS_RS21635 4697238..4697447 - 210 WP_003486601.1 CsbD family protein -
IS_RS21640 4697675..4697809 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
IS_RS21645 4697884..4698036 - 153 WP_011348912.1 entericidin A/B family lipoprotein Antitoxin
IS_RS21650 4698143..4699066 - 924 WP_008576436.1 arginase -
IS_RS21655 4699387..4699839 + 453 WP_008576438.1 roadblock/LC7 domain-containing protein -
IS_RS21660 4699903..4700262 + 360 WP_003486613.1 hypothetical protein -
IS_RS21665 4700359..4701276 + 918 WP_008576439.1 hypothetical protein -
IS_RS21670 4701273..4701815 + 543 WP_039418666.1 GTPase -
IS_RS21675 4702286..4702966 + 681 WP_011348915.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T21284 WP_005914328.1 NC_007508:c4697809-4697675 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T21284 NC_007508:c4697809-4697675 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCGGGCGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5123.06 Da        Isoelectric Point: 8.2782

>AT21284 WP_011348912.1 NC_007508:c4698036-4697884 [Xanthomonas campestris pv. vesicatoria str. 85-10]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT21284 NC_007508:c4698036-4697884 [Xanthomonas campestris pv. vesicatoria str. 85-10]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCAGGCGACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A3G2W7I0

References