Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4549294..4549829 Replicon chromosome
Accession NZ_CP081314
Organism Citrobacter farmeri strain CCRI-24236

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Cf24236_RS21715 Protein ID WP_195296289.1
Coordinates 4549542..4549829 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Cf24236_RS21710 Protein ID WP_195296290.1
Coordinates 4549294..4549545 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Cf24236_RS21680 (Cf24236_4323) 4544714..4545472 + 759 WP_195296296.1 phosphonate C-P lyase system protein PhnK -
Cf24236_RS21685 (Cf24236_4324) 4545592..4546278 + 687 WP_196014042.1 phosphonate C-P lyase system protein PhnL -
Cf24236_RS21690 (Cf24236_4325) 4546275..4547411 + 1137 WP_216525680.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
Cf24236_RS21695 (Cf24236_4326) 4547414..4547968 + 555 WP_195296293.1 ribose 1,5-bisphosphokinase -
Cf24236_RS21700 (Cf24236_4327) 4547955..4548389 + 435 WP_195505098.1 aminoalkylphosphonate N-acetyltransferase -
Cf24236_RS21705 (Cf24236_4328) 4548453..4549211 + 759 WP_216525681.1 phosphonate metabolism protein PhnP -
Cf24236_RS21710 (Cf24236_4329) 4549294..4549545 + 252 WP_195296290.1 antitoxin Antitoxin
Cf24236_RS21715 (Cf24236_4330) 4549542..4549829 + 288 WP_195296289.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Cf24236_RS21720 (Cf24236_4331) 4549826..4550155 - 330 WP_195505100.1 DDRRRQL repeat protein YjdP -
Cf24236_RS21725 (Cf24236_4332) 4550489..4552636 + 2148 WP_195505101.1 formate dehydrogenase subunit alpha -
Cf24236_RS21730 (Cf24236_4333) 4552740..4553429 + 690 WP_216525682.1 Sel1 family TPR-like repeat protein YjcO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11054.04 Da        Isoelectric Point: 10.3536

>T212814 WP_195296289.1 NZ_CP081314:4549542-4549829 [Citrobacter farmeri]
MSYTVKFREDALKEWQKLDKTIQQQFAKKLKKCCDNPHIPSAKLRGIKDCYKIKLRTSGFRLVYQVIDDVLVIAVVAVGK
REHSEVYQLASARLR

Download         Length: 288 bp

>T212814 NZ_CP107367:4170635-4170853 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9249.55 Da        Isoelectric Point: 4.1630

>AT212814 WP_195296290.1 NZ_CP081314:4549294-4549545 [Citrobacter farmeri]
MPHIILSDTTASVSELKKNPMATVNAGDGYPVAILNRNQPAFYCVPAELYEKMLDALDDQQLVKLVNERSQQPLVEVDLD
SYL

Download         Length: 252 bp

>AT212814 NZ_CP107367:4170234-4170608 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References