Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 5234254..5234759 Replicon chromosome
Accession NC_007492
Organism Pseudomonas fluorescens Pf0-1

Toxin (Protein)


Gene name relE Uniprot ID Q3K782
Locus tag PFL01_RS23285 Protein ID WP_011335833.1
Coordinates 5234505..5234759 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0C2A0X2
Locus tag PFL01_RS23280 Protein ID WP_039765667.1
Coordinates 5234254..5234508 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PFL01_RS23255 5229607..5229936 + 330 WP_007956700.1 hypothetical protein -
PFL01_RS23260 5230047..5230412 + 366 WP_011335828.1 hypothetical protein -
PFL01_RS23265 5230437..5231186 - 750 WP_011335829.1 hypothetical protein -
PFL01_RS23270 5231317..5232063 + 747 WP_011335830.1 hypothetical protein -
PFL01_RS23275 5232135..5234054 + 1920 WP_011335831.1 alkaline phosphatase family protein -
PFL01_RS23280 5234254..5234508 + 255 WP_039765667.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PFL01_RS23285 5234505..5234759 + 255 WP_011335833.1 Txe/YoeB family addiction module toxin Toxin
PFL01_RS23290 5234753..5235940 - 1188 WP_011335834.1 aspartate aminotransferase family protein -
PFL01_RS23295 5236043..5236948 + 906 WP_011335835.1 LysR family transcriptional regulator -
PFL01_RS23300 5236994..5237398 + 405 WP_011335836.1 GNAT family N-acetyltransferase -
PFL01_RS23305 5237584..5239065 + 1482 WP_011335837.1 MBOAT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9950.59 Da        Isoelectric Point: 9.6300

>T21278 WP_011335833.1 NC_007492:5234505-5234759 [Pseudomonas fluorescens Pf0-1]
MKIQFTPTGWEDYLWFQQNDKAGLKRINLLIKAIQRQPFEGLGKPEPLKHNMSGFWSRRITAEHRLVYAIVDGEICVITC
RFHY

Download         Length: 255 bp

>T21278 NC_007492:5234505-5234759 [Pseudomonas fluorescens Pf0-1]
ATGAAAATCCAGTTCACGCCAACGGGCTGGGAAGACTACTTATGGTTTCAACAAAACGATAAGGCCGGTCTCAAACGAAT
CAATCTTTTGATCAAAGCGATCCAGCGCCAACCCTTTGAAGGCTTGGGCAAACCGGAGCCGCTCAAGCACAACATGAGCG
GCTTCTGGTCACGGCGGATAACTGCCGAGCATCGCTTGGTCTATGCGATCGTAGACGGCGAAATCTGCGTCATAACTTGC
AGATTTCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9437.87 Da        Isoelectric Point: 5.1314

>AT21278 WP_039765667.1 NC_007492:5234254-5234508 [Pseudomonas fluorescens Pf0-1]
MDTINYTTARAHLAETMDRVNEDCAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGEMRAGKAKVRQ
LIEE

Download         Length: 255 bp

>AT21278 NC_007492:5234254-5234508 [Pseudomonas fluorescens Pf0-1]
ATGGACACTATCAACTACACCACAGCTCGTGCGCACTTGGCTGAAACCATGGATCGCGTGAATGAAGACTGCGCCCCGCT
TCTGGTAACCCGACAAAAAGGCGAGCCTGTAGTGATGATGTCTCTGGCCGAATACAACGCGCTGGAAGAAACGGCTTATC
TGCTGCGTTCTCCGGCCAATGCCGAGCGCTTGATCAAATCAATTGGCGAAATGCGCGCTGGAAAAGCCAAAGTCAGGCAA
CTGATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q3K782

Antitoxin

Source ID Structure
AlphaFold DB A0A0C2A0X2

References