Detailed information of TA system TA021277

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3638252..3638720
• Replicon: chromosome
• Accession: NC_007492
• Organism: Pseudomonas fluorescens Pf0-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PFL01_RS29310
• Protein ID: WP_011334552.1
• Coordinates: 3638436..3638720 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q3KBE7
• Locus tag: PFL01_RS15930
• Protein ID: WP_011334551.1
• Coordinates: 3638252..3638446 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PFL01_RS15910	3633663..3634631	-	969	WP_011334547.1	Gfo/Idh/MocA family oxidoreductase	-
PFL01_RS15915	3634641..3635528	-	888	WP_011334548.1	Dyp-type peroxidase	-
PFL01_RS15920	3635805..3636836	-	1032	WP_011334549.1	AraC family transcriptional regulator	-
PFL01_RS15925	3637049..3637996	+	948	WP_011334550.1	transporter	-
PFL01_RS15930	3638252..3638446	+	195	WP_011334551.1	hypothetical protein	Antitoxin
PFL01_RS29310	3638436..3638720	+	285	WP_011334552.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10640.01 Da
• Isoelectric Point: 9.6587

>T21277 WP_011334552.1 NC_007492:3638436-3638720 [Pseudomonas fluorescens Pf0-1]
MPLEWSDQALDDLADIIDYVEQYNSNASAALQHKVGAATQRLSSIPYGYRSGRAPGTREMVVNPNYLLVYRVNGRIKILT
LVHTRRQYPRTSST

Nucleotide

• Length: 285 bp

>T21277 NC_007492:3638436-3638720 [Pseudomonas fluorescens Pf0-1]
CTGCCGCTTGAATGGAGCGATCAAGCTCTGGACGATCTGGCTGACATTATCGATTACGTTGAACAATACAACTCCAACGC
TTCAGCGGCTCTGCAGCACAAGGTTGGTGCAGCAACGCAAAGGCTTTCATCAATCCCTTATGGTTACCGATCCGGTCGAG
CGCCAGGCACTCGGGAAATGGTGGTCAATCCGAACTATCTGCTGGTCTATCGAGTGAACGGGCGCATCAAAATACTGACG
TTAGTCCACACCCGACGACAATACCCACGAACCTCATCTACATAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7590.45 Da
• Isoelectric Point: 4.8177

>AT21277 WP_011334551.1 NC_007492:3638252-3638446 [Pseudomonas fluorescens Pf0-1]
MSILHSPFYSDFESEEEAESYDRWFRAKVQAVLDDPRPGIPHEEAMVRLDQLLEERRKNRRAAA

Nucleotide

• Length: 195 bp

>AT21277 NC_007492:3638252-3638446 [Pseudomonas fluorescens Pf0-1]
ATGAGCATATTGCATTCCCCGTTTTACTCTGACTTCGAATCCGAAGAAGAGGCAGAGAGCTACGATCGCTGGTTTCGTGC
CAAGGTGCAGGCTGTACTGGATGATCCTCGCCCGGGCATTCCCCATGAGGAAGCCATGGTGCGGCTCGACCAACTATTAG
AAGAGAGACGCAAGAATCGACGCGCTGCCGCTTGA

Structures

Antitoxin

• AlphaFold DB: A0A345RRJ8