Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yhaV-relB/YhaV(toxin)
Location 139510..140327 Replicon plasmid unnamed1
Accession NZ_CP081258
Organism Phaeobacter inhibens strain M636

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag K4L01_RS18490 Protein ID WP_260081241.1
Coordinates 139510..140028 (+) Length 173 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K4L01_RS18495 Protein ID WP_260081240.1
Coordinates 140175..140327 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K4L01_RS18465 (K4L01_18450) 135208..135597 + 390 WP_102859864.1 DUF3768 domain-containing protein -
K4L01_RS18470 (K4L01_18455) 135756..137738 + 1983 WP_260100366.1 ParB/RepB/Spo0J family partition protein -
K4L01_RS18475 (K4L01_18460) 137815..138408 + 594 WP_260081243.1 regulator -
K4L01_RS18480 (K4L01_18465) 138408..139061 + 654 WP_260100417.1 hypothetical protein -
K4L01_RS18485 (K4L01_18470) 139187..139513 + 327 WP_260081242.1 type II toxin-antitoxin system PrlF family antitoxin -
K4L01_RS18490 (K4L01_18475) 139510..140028 + 519 WP_260081241.1 type II toxin-antitoxin system YhaV family toxin Toxin
K4L01_RS18495 (K4L01_18480) 140175..140327 + 153 WP_260081240.1 StaA Antitoxin
K4L01_RS18500 (K4L01_18485) 140429..144688 + 4260 WP_260100367.1 strawberry notch family protein -
K4L01_RS18505 (K4L01_18490) 144810..145196 + 387 WP_260081238.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..169022 169022


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(19-155)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 19340.00 Da        Isoelectric Point: 9.2700

>T212757 WP_260081241.1 NZ_CP081258:139510-140028 [Phaeobacter inhibens]
MTGDSVPAQAPLVVNGWSIYAHPLFLDQLEGLIEEVEARKARDPKTWRKKNPTKRLAAIFKLVTEAIPADPGAAAFRQGG
TLGDHRKHWFRAKFFQQYRLFYRFNSDAKVIVVAWVNDDKTLRAYGSKTDAYATFKGMLDNGNPPDNFDVLLKEAAAAHE
GFEMSLEAVPDR

Download         Length: 519 bp

>T212757 NZ_CP107347:c68218-68069 [Klebsiella pneumoniae]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGTGCCACGGTATTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5360.95 Da        Isoelectric Point: 6.0760

>AT212757 WP_260081240.1 NZ_CP081258:140175-140327 [Phaeobacter inhibens]
VAADVNSYDAWFRAQLQAALDDARAGTSQVQVMQAAQALIDAKRQGQSKP

Download         Length: 153 bp

>AT212757 NZ_CP107347:68263-68322 [Klebsiella pneumoniae]
TAAGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References